2-Chloro-5-hydroxypyridine
- CAS NO.：41288-96-4
- Empirical Formula: C5H4ClNO
- Molecular Weight: 129.54
- MDL number: MFCD00234050
- EINECS: 670-289-1
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-07-24 18:13:49
What is 2-Chloro-5-hydroxypyridine?
Chemical properties
Light yellow Cryst
The Uses of 2-Chloro-5-hydroxypyridine
Used as a reagent in chemical research.
Preparation
2-Chloro-5-acetoxypyridine (21.66 g, 126 mmol) was dissolved in 300 mL of methanol and K2CO3(8.70 g, 63 mmol) was added. The reaction was stirred at room temperature for approx. 2 h, then concentrated in vacuo. The residue was diluted with diethyl ether and water, and the aqueous layer was adjusted to neutral pH by the addition of 1N aqueous HCl. Following extraction with diethyl ether, the organics were combined, washed with a solution of saturated aqueous NaCl, dried with MgSO4, and concentrated in vacuo. The resulting yellow solid (15.58 g, 96%) was used without further purification.
Properties of 2-Chloro-5-hydroxypyridine
| Melting point: | 155-158°C |
| Boiling point: | 351.9±22.0 °C(Predicted) |
| Density | 1.392±0.06 g/cm3(Predicted) |
| storage temp. | Inert atmosphere,Room Temperature |
| form | powder to crystal |
| pka | 8.69±0.10(Predicted) |
| color | Light yellow to Brown |
| CAS DataBase Reference | 41288-96-4(CAS DataBase Reference) |
Safety information for 2-Chloro-5-hydroxypyridine
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up. |
Computed Descriptors for 2-Chloro-5-hydroxypyridine
2-Chloro-5-hydroxypyridine manufacturer
GK Chemicals
1Y
Phone:+91-7207279444
Whatsapp: +91-7207279444
product: 41288-96-4 2-Chloro 5-Hydroxy Pyridine 98%
SAKEM LLP
1Y
Phone:+91-9676889998
Whatsapp: +91-9676889998
product: 41288-96-4 2-Chloro-5-Hydroxypyridine 98%
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