5-(4-Hydroxy-benzylidene)-pyrimidine-2,4,6-trione

CAS NO.：27406-31-1
Empirical Formula: C11H8N2O4
Molecular Weight: 232.19
MDL number: MFCD00117979
SAFETY DATA SHEET (SDS)
Update Date: 2026-09-12 18:49:20

What is 5-(4-Hydroxy-benzylidene)-pyrimidine-2,4,6-trione?

Biological Activity

MHY-1685, a novel mammalian target of rapamycin (mTOR) inhibitor, provides opportunities to improve hCSC-based myocardial regeneration.

References

[1]. Park JH, et al. Human cardiac stem cells rejuvenated by modulating autophagy with MHY-1685 enhance the therapeutic potential for cardiac repair. Exp Mol Med. 2021 Sep;53(9):1423-1436.

Properties of 5-(4-Hydroxy-benzylidene)-pyrimidine-2,4,6-trione

storage temp.	Store at -20°C
solubility	DMSO : 62.5 mg/mL (269.18 mM; Need ultrasonic)
form	Solid
color	Light yellow to yellow

Safety information for 5-(4-Hydroxy-benzylidene)-pyrimidine-2,4,6-trione

Computed Descriptors for 5-(4-Hydroxy-benzylidene)-pyrimidine-2,4,6-trione

New Products

5-bromo-4-fluoro-2-nitrobenzaldehyde (R)-(-)-2-Amino-1-propanol Cyclobutanone Fmoc-OSu 1-(2-Chloroethyl)pyrrolidine Hydrochloride 2-Amino-2-(4-methylphenyl)acetic acid β-Bromostyrene Ethyl 3-phenylpropanoate Phenethyl cinnamate Dipropyl disulfide 4 pentyn 1 ol N-Vinylformamide Methacrylate-PEG-Methacrylate, Mn:35000 2,4-Dihydroxyacetophenone 2-Chloro 5-Fluoro Pyridine Vasicinone 2-Chloroisonicotinic Acid Tween 80 or Polysorbate 80 2-Butyn-1-oL 2-Pentyn-1-oL 4-Nitrobenzotrifluoride N-(4-fluoro-2-methoxy-5-nitrophenyl)-4-(1-methyl-1H-indol-3-yl)pyrimidin-2-amine Pirtobrutinib intd. N-(4-Cyano-3-(trifluoromethyl)phenyl)-2-methyloxirane-2-carboxamide