5-(2-BENZOTHIAZOLYL)-3-ETHYL-2-(-(METHY
Synonym(s):Akt Inhibitor IV - CAS 681281-88-9 - Calbiochem
- CAS NO.：681281-88-9
- Empirical Formula: C31H27N4S.I
- Molecular Weight: 614.548
- MDL number: MFCD00570739
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-05-28 03:44:45
What is 5-(2-BENZOTHIAZOLYL)-3-ETHYL-2-(-(METHY?
The Uses of 5-(2-BENZOTHIAZOLYL)-3-ETHYL-2-(-(METHY
Akt Inhibitor IV is an Inhibitor of Akt protein kinase
What are the applications of Application
Akt Inhibitor IV is an Inhibitor of Akt protein kinase
Biological Activity
akt inhibitor iv is an inhibitor of akt activation that inhibits akt-mediated nuclear export of forkhead box class o transcription factor 1a (foxo1a; ic50 = 625 nm) and reduces phosphorylation of akt at ser473 and thr308 in a dose-dependent manner. akt inhibitor iv inhibits replication of parainfluenza virus 5 (piv5) in hela cells (ic50 = 520 nm). it also reduces the growth of cancer cells (ic50 = 0.3 μm for both jurkat and hela cells) via a reduction in mitochondrial polarization and increased production of reactive oxygen species (ros).
Properties of 5-(2-BENZOTHIAZOLYL)-3-ETHYL-2-(-(METHY
| storage temp. | 2-8°C |
| solubility | DMSO: ≥10 mg/mL |
| form | solid |
| color | orange |
Safety information for 5-(2-BENZOTHIAZOLYL)-3-ETHYL-2-(-(METHY
Computed Descriptors for 5-(2-BENZOTHIAZOLYL)-3-ETHYL-2-(-(METHY
| InChIKey | NAYRELMNTQSBIN-UHFFFAOYSA-M |
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