4,4-DIMETHYL-2-PHENYL-2-OXAZOLINE
- CAS NO.：19312-06-2
- Empirical Formula: C11H13NO
- Molecular Weight: 175.23
- MDL number: MFCD00030446
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:23:54
What is 4,4-DIMETHYL-2-PHENYL-2-OXAZOLINE?
The Uses of 4,4-DIMETHYL-2-PHENYL-2-OXAZOLINE
4,4-Dimethyl-2-phenyl-2-oxazoline may be used in the synthesis of an ester-ammonium salt via rupture of oxazoline ring.
Synthesis Reference(s)
Journal of the American Chemical Society, 82, p. 2032, 1960 DOI: 10.1021/ja01493a045
Tetrahedron Letters, 27, p. 5269, 1986 DOI: 10.1016/S0040-4039(00)85187-4
General Description
4,4-Dimethyl-2-phenyl-2-oxazoline is an 2-aryl-2-oxazoline and has been tested as as ligand for the Suzuki coupling reaction of aryl bromides and arylboronic acids. 4,4-Dimethyl-2-phenyl-2-oxazoline forms mildly hygroscopic complexes, of general formulae [ZnX2(ox)2] (ox =4,4-Dimethyl-2-phenyl-2-oxazoline), with ether solutions of [ZnX2] (X = Cl, Br, I).Except ZnI2, which does not form an isolable complex due to steric reasons.
Properties of 4,4-DIMETHYL-2-PHENYL-2-OXAZOLINE
| Melting point: | 20-24 °C(lit.) |
| Boiling point: | 124 °C20 mm Hg(lit.) |
| Density | 1.025 g/mL at 25 °C(lit.) |
| refractive index | n |
| Flash point: | 217 °F |
| pka | 4.82±0.70(Predicted) |
| BRN | 132225 |
Safety information for 4,4-DIMETHYL-2-PHENYL-2-OXAZOLINE
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P321:Specific treatment (see … on this label). P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P332+P313:IF SKIN irritation occurs: Get medical advice/attention. P337+P313:IF eye irritation persists: Get medical advice/attention. |
Computed Descriptors for 4,4-DIMETHYL-2-PHENYL-2-OXAZOLINE
New Products
Pentadecanoic acid 3-Bromophenylacetic acid 3-AMINO-3-(2-FLUORO-PHENYL)-PROPIONIC ACID Hendecanoic acid 2-Amino-5-cyanopyridine 2-Bromo-5-cyanopyridine 4-(4-(Dimethylamino)-1-(4-fluorophenyl)-1-hydroxybutyl)-3-(hydroxymethyl)benzonitrile 3′-Hydroxyacetophenone 5-fluoro-1,3-benzodioxole 5-Bromo-4-chloro-3-indolyl-β-D-galactopyranoside Tetracaine Hydrochloride Ep Grade 2,2,2-Trichloroethyl chloroformate 2-Bromo-6-fluoroaniline 2-Amino-4-phenyl-thiazole 4-Chloro-2-methyl quinoline 2-(Chloromethyl) quinazolin-4(3H)-one 5-Phenyl-[1,3,4]-thiadiazol-2-amine 2-Chloro-6-nitro benzothiazole N-(4-Bromophenyl)-2-chloroacetamide 6-Isopropylpicolinonitrile N-Methyl-3,5-dinitro-2-pyridinamine Phenyl-boronic acid-d5 10,11-Dihdyro-10-oxo-5H-dibenz[b,f]azepine-5-carboxamide-d4 5-(2,4-difluorophenyl)oxazolidin-2-oneRelated products of tetrahydrofuran
![1-BENZOTHIEN-2-YL[2-(4,4-DIMETHYL-4,5-DIHYDRO-1,3-OXAZOL-2-YL)PHENYL]METHANOL](https://img.chemicalbook.in/StructureFile/ChemBookStructure6/GIF/CB8693806.gif)
![2-[1-(3,5-DIMETHYLPHENYL)-2-NAPHTHYL]-4,5-DIHYDRO-4,4-DIMETHYLOXAZOLE](https://img.chemicalbook.in/StructureFile/ChemBookStructure2/GIF/CB7312548.gif)
You may like
-
Deuterated Styrene-d8 97-99%View Details
19361-62-7 -
1620885-59-7 3-bromo-[1,1'-biphenyl]-2-amine 97-99%View Details
1620885-59-7 -
1503408-77-2 6-Chloro-3,4-dimethylpyridin-2-amine 97-99%View Details
1503408-77-2 -
665020-24-6 ethyl 1-(2,4-dichlorophenyl)-4,5-dihydro-1H-benzo[g]indazole-3-carboxylate 97-99%View Details
665020-24-6 -
1187989-89-4 97-99%View Details
1187989-89-4 -
Methyl 1-(2,2,2-trifluoroethyl)azetidine-3-carboxylate 97-99%View Details
1872090-65-7 -
32659-49-7 97-99%View Details
32659-49-7 -
212322-17-3 methyl 3-amino-4-formylbenzoate 97-99%View Details
212322-17-3
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.