4,4'-DIMETHOXYBENZHYDROL
Synonym(s):Bis(4-methoxyphenyl)carbinol
- CAS NO.：728-87-0
- Empirical Formula: C15H16O3
- Molecular Weight: 244.29
- MDL number: MFCD00008410
- EINECS: 211-975-9
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-05-27 22:37:05
What is 4,4'-DIMETHOXYBENZHYDROL?
Chemical properties
white to off-white crystalline powder
The Uses of 4,4'-DIMETHOXYBENZHYDROL
4,4?-Dimethoxybenzhydrol was used to study the kinetics and mechanism of oxidation of substituted benzhydrols to corresponding benzophenones in the presence of Hg(OAc)2 by N-bromosuccinimide. It is useful in the protection of glutamine and asparagine residues in peptide synthesis, reagent for the N-protection of amides.
General Description
4,4′-Dimethoxybenzhydrol causes N-alkylation of amides, lactams, carbamates, ureas and anilines in acetic acid during H2SO4 catalysis.
Properties of 4,4'-DIMETHOXYBENZHYDROL
| Melting point: | 67-70 °C(lit.) |
| Boiling point: | 347.2°C (rough estimate) |
| Density | 1.1263 (rough estimate) |
| refractive index | 1.5570 (estimate) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | methanol: 0.1 g/mL, clear |
| pka | 13.68±0.20(Predicted) |
| form | Solid |
| color | White |
| Water Solubility | Soluble in water (0.44 g/L @ 25°C), methanol (0.1 g/mL). |
| BRN | 748532 |
| CAS DataBase Reference | 728-87-0(CAS DataBase Reference) |
Safety information for 4,4'-DIMETHOXYBENZHYDROL
Computed Descriptors for 4,4'-DIMETHOXYBENZHYDROL
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