4-PENTYNOIC ACID

Chemical properties

white to beige crystalline powder or flakes

The Uses of 4-PENTYNOIC ACID

4-Pentynoic Acid is a hypoglycemic agent shown to increase liver tyrosine aminotransferase and plasma corticosterone while decreasing blood sugar in rats.

The Uses of 4-PENTYNOIC ACID

4-Pentynoic acid was used:

• as building block for the synthesis of library of eight sequence-defined model oligomers
• in one-pot synthesis of the complex polycyclic heterocycles benzo[4,5]imidazo[1,2-c]pyrrolo[1,2-a]quinazolinone derivatives
• in the synthesis of various allenenols lactones [5(E)-(2-allenylidene)-tetrahydro-2-furanones]
• in the synthesis of a cyctotoxic macrolide by ring-closing metathesis of a bis acetylene

What are the applications of Application

4-Pentynoic acid is a building block for sequence-defined model oligomers

General Description

4-Pentynoic acid undergoes copper-catalyzed intramolecular cyclizations to form enol lactones. It also reacts with 1-bromo-1-alkynes in the presence of a Pd catalyst to yield biologically active ynenol lactones.