4-P-PDOT
Synonym(s):4-Phenyl-2-propionamidotetralin;4P-PDOT;AH 024;cis-4-Phenyl-2-propionamidotetralin;N-(1,2,3,4-Tetrahydro-4-phenyl-2-naphthalenyl)-propanamide
- CAS NO.：134865-74-0
- Empirical Formula: C19H21NO
- Molecular Weight: 279.38
- MDL number: MFCD00901545
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-07-27 17:00:41
What is 4-P-PDOT?
The Uses of 4-P-PDOT
4-P-PDOT is a MT2 melatonin receptor ligand.
What are the applications of Application
4-P-PDOT is a MEL-1B-R melatonin receptor antagonist
Definition
ChEBI: N-(4-phenyl-1,2,3,4-tetrahydronaphthalen-2-yl)propanamide is a member of tetralins.
Biological Activity
Melatonin receptor antagonist, >300-fold selective for the MT 2 (vs MT 1 ) subtype.
Biochem/physiol Actions
4-P-PDOT is a slelctive MT2 melatonin receptor antagonist 300 fold selective for MT2 (MEL-1B-R) vs MT1 (MEL-1A-R) melatonin receptor subtype.
Properties of 4-P-PDOT
| Melting point: | 166 °C |
| Boiling point: | 480.1±45.0 °C(Predicted) |
| Density | 1.11±0.1 g/cm3(Predicted) |
| storage temp. | room temp |
| solubility | Soluble in DMSO > 10 mM |
| pka | 15.87±0.40(Predicted) |
| form | powder |
| color | white to beige |
Safety information for 4-P-PDOT
Computed Descriptors for 4-P-PDOT
New Products
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