4-O-(Carboxymethyl)rifamycin
- CAS NO.：13929-35-6
- Empirical Formula: C39H49NO14
- Molecular Weight: 755.8
- EINECS: 237-697-8
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-05-15 10:43:33
What is 4-O-(Carboxymethyl)rifamycin?
The Uses of 4-O-(Carboxymethyl)rifamycin
A Rifamycin (R508200) derivative as antibacterial agent.
The Uses of 4-O-(Carboxymethyl)rifamycin
Rifamycin B (Rifaximin EP Impurity B) is a Rifamycin (R508200) derivative as antibacterial agent.
What are the applications of Application
Rifamycin B is Rifamycin B is a Rifamycin derivative used as antibacterial agent
Definition
ChEBI: Rifamycin B is a carboxylic acid, an acetate ester, an organic heterotetracyclic compound and a member of rifamycins. It is a conjugate acid of a rifamycin B(2-).
Purification Methods
Rifamycin B forms yellow needles from *C6H6. Its solubilities are: H2O (0,027%), MeOH (2.62%) and EtOH (0.44%). It has UV max at 223, 304 and 245nm (A 1cm 555, 275 and 220). [Oppolzer & Prelog Helv Chim Acta 56 2287 1973, Oppolzer et al. Experientia 20 336 1964, X-ray: Brufani et al. Experientia 20 339 1964.]
Properties of 4-O-(Carboxymethyl)rifamycin
| Melting point: | 300° (dec 160-164°) |
| Boiling point: | 730.16°C (rough estimate) |
| alpha | D20 -11° (methanol) |
| Density | 1.2421 (rough estimate) |
| refractive index | 1.5350 (estimate) |
| solubility | DMSO (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly, Sonicated) |
| form | neat |
| pka | 2.69±0.10(Predicted) |
| BRN | 604953 |
| Stability: | Unstable in solution |
Safety information for 4-O-(Carboxymethyl)rifamycin
Computed Descriptors for 4-O-(Carboxymethyl)rifamycin
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