4-Nitropyridine N-oxide
- CAS NO.：1124-33-0
- Empirical Formula: C5H4N2O3
- Molecular Weight: 140.1
- MDL number: MFCD00006206
- EINECS: 214-395-4
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-09-25 17:15:13
What is 4-Nitropyridine N-oxide?
Chemical properties
white to light yellow crystal
The Uses of 4-Nitropyridine N-oxide
The N-oxide derivative of a nitrated pyridine that has been shown to inhibit Na,K-ATPase activity. 4-Nitropyridine N-Oxide is a quorum sensing inhibitor.
The Uses of 4-Nitropyridine N-oxide
4-Nitropyridine N-oxide may be used in the preparation of several 4-substituted pyridine-N-oxides and pyridines.
What are the applications of Application
4-Nitropyridine N-oxide is a quorum-sensing inhibitor
General Description
Solid.
Air & Water Reactions
May be deliquescent.
Reactivity Profile
Aromatic nitro compounds range from slight to strong oxidizing agents. If mixed with reducing agents, including hydrides, sulfides and nitrides, they may begin a vigorous reaction.
Health Hazard
High toxicity via oral exposure.
Fire Hazard
When heated to decomposition, 4-Nitropyridine N-oxide emits very toxic fumes of nitrogen oxides. Avoid decomposing heat.
Safety Profile
Poison by ingestion and skincontact. Questionable carcinogen with experimentaltumorigenic data. Mutation data reported. Mixtures withdiethyl-1,4-dihydro-2,6-dimethylpyridine-3,5-dicarboxylateexplode when heated above 130°C. When heated todecompositio
Properties of 4-Nitropyridine N-oxide
| Melting point: | 159-162 °C (lit.) |
| Boiling point: | 256.56°C (rough estimate) |
| Density | 1.5657 (rough estimate) |
| refractive index | 1.4800 (estimate) |
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | soluble in DMSO |
| pka | -1.37±0.10(Predicted) |
| form | Crystals or Powder |
| color | Yellow to brown |
| Water Solubility | insoluble |
| BRN | 124331 |
| CAS DataBase Reference | 1124-33-0(CAS DataBase Reference) |
| NIST Chemistry Reference | Pyridine-1-oxide, 4-nitro-(1124-33-0) |
| EPA Substance Registry System | 4-Nitropyridine-1-oxide (1124-33-0) |
Safety information for 4-Nitropyridine N-oxide
| Signal word | Danger |
| Pictogram(s) |
 Skull and Crossbones Acute Toxicity GHS06  Health Hazard GHS08 |
| GHS Hazard Statements |
H300:Acute toxicity,oral H301:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation H341:Germ cell mutagenicity |
| Precautionary Statement Codes |
P201:Obtain special instructions before use. P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P301+P310:IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up. |
Computed Descriptors for 4-Nitropyridine N-oxide
4-Nitropyridine N-oxide manufacturer
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GK Chemicals
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product: 4-Nitro Pyridine-N-Oxide 1124-33-0 98%
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