4-(N-Maleimido)benzophenone
Synonym(s):Benzophenone-4-maleimide
- CAS NO.：92944-71-3
- Empirical Formula: C17H11NO3
- Molecular Weight: 277.27
- MDL number: MFCD00079465
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-04-24 14:58:06
What is 4-(N-Maleimido)benzophenone?
Chemical properties
Light Beige Solid
The Uses of 4-(N-Maleimido)benzophenone
4-(N-Maleimido)benzophenone can be used as a sulfhydryl reactive heterobifunctional photocrosslinking reagent. It generates photoactivatable conjugates from thiols
The Uses of 4-(N-Maleimido)benzophenone
Maleimide-containing benzophenone as photoinitiator
The Uses of 4-(N-Maleimido)benzophenone
A heterobifunctional cross-linking reagent containing a sulfhydryl-specific group and a photo-active group. Typically, coupled initially by thioether to molecule containing free sulfhydryl buffered at pH 6.8 (6.5-7.0). Second bonding occurs during UV irradiation (250 nm) via diradical excited state. Benzophenones demonstrate greater specificity for C-H insertion and are more stable in water than analogous reagents. In general they are more efficient in attachment because they may be repeatedly irradiated; however, a more intense irradiation may be required. The benzophenone is not sensitive to
What are the applications of Application
4-(Maleimido)benzophenone is a benzophenone-based, sulfhydryl-reactive photoreactive crosslinker
Properties of 4-(N-Maleimido)benzophenone
| Melting point: | 155-157°C |
| Boiling point: | 472.9±28.0 °C(Predicted) |
| Density | 1.330±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | chloroform: 50 mg/mL |
| form | Solid |
| pka | -3.80±0.20(Predicted) |
| color | Light Beige |
Safety information for 4-(N-Maleimido)benzophenone
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 4-(N-Maleimido)benzophenone
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