4-Methoxyfuro[2,3-b]quinolin-8-ol
- CAS NO.:2255-50-7
- Empirical Formula: C12H9NO3
- Molecular Weight: 215.2
- MDL number: MFCD01545265
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-03-13 15:00:32
What is 4-Methoxyfuro[2,3-b]quinolin-8-ol?
Description
Haplophyllum robustum Bge. yields this alkaloid which forms colourless crystals from EtOH. It forms a series of crystalline salts and derivatives including the hydrochloride, m.p. 199-200°C; picrate, m.p. I 79-180°C; acetyl derivative, m.p.174-5°C; methyl derivative, m.p. 140-2°C and the tetrahydrG compound with m.p.201-2°C.
Definition
ChEBI: A quinoline alkaloid that is furo[2,3-b]quinoline substituted by a methoxy and a hydroxy group at positions 4 and 8 respectively.
References
Fakhritdinova, Sidyakin, Yunusov,Khim. Prir.Soedin., 1, 107 (1965)
Faizutdinova, Yunusov, ibid, 3, 260 (1967)
Narasimhan, Paradkar, Alurkar, Tetrahedron, 27,1351 (1971)
Properties of 4-Methoxyfuro[2,3-b]quinolin-8-ol
| Melting point: | 148-149℃ (ethanol ) |
| Boiling point: | 411.9±40.0 °C(Predicted) |
| Density | 1.378±0.06 g/cm3(Predicted) |
| storage temp. | 4°C, protect from light |
| form | Solid |
| pka | 5.34±0.30(Predicted) |
| color | White to off-white |
Safety information for 4-Methoxyfuro[2,3-b]quinolin-8-ol
| Signal word | Danger |
| Pictogram(s) |
![]() Corrosion Corrosives GHS05 ![]() Exclamation Mark Irritant GHS07 ![]() Environment GHS09 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H314:Skin corrosion/irritation H317:Sensitisation, Skin H410:Hazardous to the aquatic environment, long-term hazard |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P272:Contaminated work clothing should not be allowed out of the workplace. P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P391:Collect spillage. Hazardous to the aquatic environment P301+P330+P331:IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P333+P313:IF SKIN irritation or rash occurs: Get medical advice/attention. P405:Store locked up. |
Computed Descriptors for 4-Methoxyfuro[2,3-b]quinolin-8-ol
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