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HomeProduct name list4-Methoxyfuro[2,3-b]quinolin-8-ol

4-Methoxyfuro[2,3-b]quinolin-8-ol

4-Methoxyfuro[2,3-b]quinolin-8-ol Structural

What is 4-Methoxyfuro[2,3-b]quinolin-8-ol?

Description

Haplophyllum robustum Bge. yields this alkaloid which forms colourless crystals from EtOH. It forms a series of crystalline salts and derivatives including the hydrochloride, m.p. 199-200°C; picrate, m.p. I 79-180°C; acetyl derivative, m.p.174-5°C; methyl derivative, m.p. 140-2°C and the tetrahydrG compound with m.p.201-2°C.

Definition

ChEBI: A quinoline alkaloid that is furo[2,3-b]quinoline substituted by a methoxy and a hydroxy group at positions 4 and 8 respectively.

References

Fakhritdinova, Sidyakin, Yunusov,Khim. Prir.Soedin., 1, 107 (1965)
Faizutdinova, Yunusov, ibid, 3, 260 (1967)
Narasimhan, Paradkar, Alurkar, Tetrahedron, 27,1351 (1971)

Properties of 4-Methoxyfuro[2,3-b]quinolin-8-ol

Melting point: 148-149℃ (ethanol )
Boiling point: 411.9±40.0 °C(Predicted)
Density  1.378±0.06 g/cm3(Predicted)
storage temp.  4°C, protect from light
form  Solid
pka 5.34±0.30(Predicted)
color  White to off-white

Safety information for 4-Methoxyfuro[2,3-b]quinolin-8-ol

Signal word Danger
Pictogram(s)
ghs
Corrosion
Corrosives
GHS05
ghs
Exclamation Mark
Irritant
GHS07
ghs
Environment
GHS09
GHS Hazard Statements H302:Acute toxicity,oral
H314:Skin corrosion/irritation
H317:Sensitisation, Skin
H410:Hazardous to the aquatic environment, long-term hazard
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P264:Wash hands thoroughly after handling.
P264:Wash skin thouroughly after handling.
P270:Do not eat, drink or smoke when using this product.
P272:Contaminated work clothing should not be allowed out of the workplace.
P273:Avoid release to the environment.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P391:Collect spillage. Hazardous to the aquatic environment
P301+P330+P331:IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P333+P313:IF SKIN irritation or rash occurs: Get medical advice/attention.
P405:Store locked up.

Computed Descriptors for 4-Methoxyfuro[2,3-b]quinolin-8-ol

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