4-HYDROXYESTRONE
Synonym(s):1,3,5(10)-Estratriene-3,4-diol-17-one
- CAS NO.：3131-23-5
- Empirical Formula: C18H22O3
- Molecular Weight: 286.37
- MDL number: MFCD00079358
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-05-20 15:44:55
What is 4-HYDROXYESTRONE?
Chemical properties
Pale Yellow Solid
The Uses of 4-HYDROXYESTRONE
A metabolite of Estradiol
The Uses of 4-HYDROXYESTRONE
A metabolite of Estradiol.
What are the applications of Application
4-Hydroxy Estrone is An Estradiol metabolite
Definition
ChEBI: A 4-hydroxy steroid that is estrone substituted by a hydroxy group at position 4.
Hazard
A reproductive hazard.
Biochem/physiol Actions
4-Hydroxyestrone is an endogenous estrogen metabolite, which exhibits a strong neuroprotective effect against oxidative damage. It also provides effective protection against kanic acid-induced hippocampal oxidative damage in rats when compared to 17β-estradiol. 4-Hydroxyestrone regulates the angiogenic process during corpus luteum formation. It might be involved in an increased risk of cancer. 4-Hydroxyestrone is found in the early and mid-luteal phases.
Properties of 4-HYDROXYESTRONE
| Melting point: | 260-263°C |
| Boiling point: | 468.2±45.0 °C(Predicted) |
| Density | 1.241±0.06 g/cm3(Predicted) |
| Flash point: | 93 °C |
| storage temp. | −20°C |
| solubility | DMSO (Slightly), Ethanol (Slightly, Sonicated), Methanol (Slightly) |
| form | Solid |
| pka | 10.06±0.40(Predicted) |
| color | Pale Yellow to Light Brown |
Safety information for 4-HYDROXYESTRONE
Computed Descriptors for 4-HYDROXYESTRONE
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