4-Fluorophenylacetyl chloride
- CAS NO.：459-04-1
- Empirical Formula: C8H6ClFO
- Molecular Weight: 172.58
- MDL number: MFCD00674181
- EINECS: 628-331-1
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:26:28
What is 4-Fluorophenylacetyl chloride?
Chemical properties
clear yellow liquid
The Uses of 4-Fluorophenylacetyl chloride
4-Fluorophenylacetyl chloride is used as an acylating agent in organic synthesis. It is used to prepare monoacylated pyrazolidine by reacting with pyrazolidine. It is also used in the preparation of N-acyl isothiouronium chloride.
The Uses of 4-Fluorophenylacetyl chloride
4-Fluorophenylacetyl chloride may be used in the preparation of bicyclic pyrazolones and dihydropyrrol-2-ones.
Properties of 4-Fluorophenylacetyl chloride
| Melting point: | 47-48 |
| Boiling point: | 60 °C/8 mmHg (lit.) |
| Density | 1.259 g/mL at 25 °C (lit.) |
| refractive index | 1.511-1.513 |
| Flash point: | 107 °C |
| storage temp. | 2-8°C |
| solubility | Miscible with dichloromethane. |
| form | Liquid |
| Specific Gravity | 1.259 |
| color | Clear yellow |
| Sensitive | Moisture Sensitive |
| BRN | 972148 |
| CAS DataBase Reference | 459-04-1(CAS DataBase Reference) |
Safety information for 4-Fluorophenylacetyl chloride
| Signal word | Danger |
| Pictogram(s) |
 Corrosion Corrosives GHS05 |
| GHS Hazard Statements |
H314:Skin corrosion/irritation H318:Serious eye damage/eye irritation |
| Precautionary Statement Codes |
P280:Wear protective gloves/protective clothing/eye protection/face protection. P310:Immediately call a POISON CENTER or doctor/physician. P301+P330+P331:IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up. |
Computed Descriptors for 4-Fluorophenylacetyl chloride
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