4-Ethynylaniline

Synonym(s):1-Amino-4-ethynylbenzene;P-APAC

CAS NO.：14235-81-5
Empirical Formula: C8H7N
Molecular Weight: 117.15
MDL number: MFCD00168824
SAFETY DATA SHEET (SDS)
Update Date: 2026-09-12 18:49:11

What is 4-Ethynylaniline?

Chemical properties

White or light yellow solid

The Uses of 4-Ethynylaniline

4-Ethynylaniline may be used in the synthesis of N-methyliminodiethyl 4-(4-ethynylphenyliminomethyl)benzeneboronate. It can also be used to prepare an acetylene ligand, HC₂-NDI (NDI= 1,4,5,8-naphthalenediimide).

What are the applications of Application

4-Ethynylaniline is an alkyne component in indole synthesis

Definition

ChEBI: 4-ethynylaniline is a substituted aniline.

Synthesis Reference(s)

The Journal of Organic Chemistry, 59, p. 5818, 1994 DOI: 10.1021/jo00098a051

General Description

4-Ethynylaniline, also known as p-ethynylaniline, is a terminal alkyne. Its synthesis using 2-methyl-3-butyn-2-ol (MEBYNOL) has been reported. The transition metal catalyzed polymerization of 4-ethynylaniline to afford poly(4-ethynylaniline) has been reported. The impact of the surface functionalization with 4-ethynylaniline on the thermal behavior of multi-walled carbon nanotubes (MWNTs) and graphene has been investigated.

Properties of 4-Ethynylaniline

Melting point:	98-102 °C (dec.) (lit.)
Boiling point:	99-101 °C(Press: 13 Torr)
Density	1.05±0.1 g/cm3(Predicted)
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
form	Crystalline Powder
pka	3.11±0.10(Predicted)
color	Yellow to brown
BRN	2205181
CAS DataBase Reference	14235-81-5(CAS DataBase Reference)

Safety information for 4-Ethynylaniline

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.