4-Difluoromethoxy-3-hydroxybenzaldehyde
Synonym(s):3-Hydroxy-4-difluoromethoxybenzaldehyde
- CAS NO.：151103-08-1
- Empirical Formula: C8H6F2O3
- Molecular Weight: 188.13
- MDL number: MFCD04406687
- EINECS: 687-745-0
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:16:56
What is 4-Difluoromethoxy-3-hydroxybenzaldehyde?
Chemical properties
4-Difluoromethoxy-3-hydroxybenzaldehyde is white powder
The Uses of 4-Difluoromethoxy-3-hydroxybenzaldehyde
4-Difluoromethoxy-3-hydroxybenzaldehyde is a phenyl alkyl ketone derivative used in the preparation of phosphodiesterase-4 (PDE4) inhibitors.
Properties of 4-Difluoromethoxy-3-hydroxybenzaldehyde
| Melting point: | 85-90°C |
| Boiling point: | 280.6±35.0 °C(Predicted) |
| Density | 1.395±0.06 g/cm3(Predicted) |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| solubility | Chloroform (Slightly), Methanol (Slightly) |
| form | Solid |
| pka | 7.85±0.35(Predicted) |
| color | White |
| CAS DataBase Reference | 151103-08-1(CAS DataBase Reference) |
Safety information for 4-Difluoromethoxy-3-hydroxybenzaldehyde
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07  Environment GHS09 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation H411:Hazardous to the aquatic environment, long-term hazard |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P273:Avoid release to the environment. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 4-Difluoromethoxy-3-hydroxybenzaldehyde
| InChIKey | ZLIKNROJGXXNJG-UHFFFAOYSA-N |
4-Difluoromethoxy-3-hydroxybenzaldehyde manufacturer
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product: 4-Difluoromethoxy-3-hydroxybenzaldehyde 151103-08-1 98+
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