(Trifluoromethoxy)benzene
Synonym(s):α,α,α-Trifluoroanisole;Phenyl trifluoromethyl ether
- CAS NO.：456-55-3
- Empirical Formula: C7H5F3O
- Molecular Weight: 162.11
- MDL number: MFCD00040832
- EINECS: 207-269-5
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-04-24 14:58:33
What is (Trifluoromethoxy)benzene?
Chemical properties
Colorless to light yellow liqui
Synthesis Reference(s)
The Journal of Organic Chemistry, 29, p. 1, 1964 DOI: 10.1021/jo01024a001
General Description
(Trifluoromethoxy)benzene is an aryl trifluoromethyl ether. (Trifluoromethoxy)benzene can be prepared from 4-chloro-1-(trifluoromethoxy)benzene via hydrogenolysis. Conformation of (trifluoromethoxy)benzene in the gas phase has been studied by electron diffraction and spectroscopy supplemented with ab initio calculations.
Properties of (Trifluoromethoxy)benzene
| Melting point: | -49.9°C |
| Boiling point: | 102 °C(lit.) |
| Density | 1.226 g/mL at 25 °C(lit.) |
| vapor pressure | 41.3 mm Hg ( 25 °C) |
| refractive index | n |
| Flash point: | 54 °F |
| storage temp. | Sealed in dry,2-8°C |
| form | clear liquid |
| color | Colorless to Almost colorless |
| Specific Gravity | 1.226 |
| BRN | 2043132 |
| CAS DataBase Reference | 456-55-3(CAS DataBase Reference) |
| NIST Chemistry Reference | Trifluoromethoxybenzene(456-55-3) |
| EPA Substance Registry System | (Trifluoromethoxy)benzene (456-55-3) |
Safety information for (Trifluoromethoxy)benzene
| Signal word | Danger |
| Pictogram(s) |
 Flame Flammables GHS02  Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H225:Flammable liquids H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for (Trifluoromethoxy)benzene
| InChIKey | GQHWSLKNULCZGI-UHFFFAOYSA-N |
New Products
2-(2-Ethoxyphenoxy)ethyl bromide 1,3-Dibromo-2,2-dimethoxypropane 8-Bromo-7-(2-butynyl)-3-methyl xanthine 5-Chlorothiophene-2-carboxylic acid 8-Bromo-3-methyl xanthine Maleic hydrazide o-Anisaldehyde 4-Bromobenzaldehyde 3-Fluorobenzaldehyde 2-Chlorobenzaldehyde 3-Amino-3-(3-fluorophenyl)propanoic acid 1-Propyl-4-piperidone 2,3-Dihydro-5,6-dimethoxy-2-(4-piperidinylmethyl)-1H-inden-1-one hydrochloride 3-(4-Bromo-3-methyl-2-oxo-2,3-dihydro-1h-benzo[d]imidazol-1-yl)piperidine-2,6-dione 2-Fluoro-6-iodobenzoic acid 3-Pyridineacrylic acid 1-Boc-4-cyanopiperidine ethyl 2-oxo-2,3,9,10-tetrahydro-1H-pyrido[3',4':4,5]pyrrolo[1,2,3-de]quinoxaline-8(7H)-carboxylate Vardenafil Bis-sulphonamide(Dimer) Nitroso Irbesartan N-Nitroso Nortriptyline Sulfonic acid Impurity 2-(p-Tolyl)acetaldehyde 2,2-dibromo-1-cyclopropyl-2-(2-fluorophenyl)ethan-1-oneRelated products of tetrahydrofuran
You may like
-
(Trifluoromethoxy)benzene CAS 456-55-3View Details
456-55-3 -
(Trifluoromethoxy)benzene CAS 456-55-3View Details
456-55-3 -
Deuterated Styrene-d8 19361-62-7 97-99%View Details
19361-62-7 -
1187989-89-4 97-99%View Details
1187989-89-4 -
(S)-2-Bromobutanoic acid 97-99%View Details
32659-49-7 -
665020-24-6 ethyl 1-(2,4-dichlorophenyl)-4,5-dihydro-1H-benzo[g]indazole-3-carboxylate 97-99%View Details
665020-24-6 -
3-bromo-[1,1'-biphenyl]-2-amine 1620885-59-7 97-99%View Details
1620885-59-7 -
1503408-77-2 6-Chloro-3,4-dimethylpyridin-2-amine 97-99%View Details
1503408-77-2
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.