4-chloro-7-Methoxyquinoline-6-carboxaMide
- CAS NO.：417721-36-9
- Empirical Formula: C11H9ClN2O2
- Molecular Weight: 236.65
- MDL number: MFCD13192256
- EINECS: 000-000-0
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-05-27 23:19:10
What is 4-chloro-7-Methoxyquinoline-6-carboxaMide?
Description
4-chloro-7-Methoxyquinoline-6-carboxaMide is a pharmaceutical intermediate compound used in the preparation of Lenvatinib, an oral multi-receptor tyrosine kinase inhibitor approved by the FDA for the treatment of radioiodine-refractory differentiated thyroid cancer (DTC), unresectable (DTC), unresectable hepatocellular carcinoma (HCC), and advanced renal cell carcinoma (RCC).
Chemical properties
light yellow powder
The Uses of 4-chloro-7-Methoxyquinoline-6-carboxaMide
Pharmaceutical Intermediates. 4-chloro-7-Methoxyquinoline-6-carboxaMide is used as an intermediate for synthesizing Lenvatinibis.
Properties of 4-chloro-7-Methoxyquinoline-6-carboxaMide
| Melting point: | >205°C (dec.) |
| Boiling point: | 426.7±45.0 °C(Predicted) |
| Density | 1.380±0.06 g/cm3(Predicted) |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| form | Solid |
| pka | 15.28±0.30(Predicted) |
| color | Off-White to Light Beige |
| InChI | InChI=1S/C11H9ClN2O2/c1-16-10-5-9-6(4-7(10)11(13)15)8(12)2-3-14-9/h2-5H,1H3,(H2,13,15) |
| CAS DataBase Reference | 417721-36-9 |
Safety information for 4-chloro-7-Methoxyquinoline-6-carboxaMide
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 4-chloro-7-Methoxyquinoline-6-carboxaMide
| InChIKey | ZBTVNIDMGKZSGC-UHFFFAOYSA-N |
| SMILES | N1C2C(=CC(C(N)=O)=C(OC)C=2)C(Cl)=CC=1 |
4-chloro-7-Methoxyquinoline-6-carboxaMide manufacturer
BTC pharm India
5Y
Phone:+91-8790379245
Whatsapp: +91- 6361382515
product: 417721-36-9 4-Chloro-7-Methoxyquinoline-6-Carboxamide 98+
Archerchem Healthcare Pvt., Ltd. (part of Archerchem Group)
Maharashtra
product: 4-Chloro-7-methoxyquinoline-6-carboxamide
New Products
Dibenzoyl-L-tartaric acid Anhydrous (Resolution Reagent) Cis-Tosylate Dibenzo[b,f][1,4]thiazepin-11(10H)-one 1,2,3,9-Tetrahydro-9-Methyl-4H-Carbazole-4-One 1-(4-methoxyphenyl)-4-(4-Nitrophenyl)Piperazine (IT-1) BOC Piperazine 1-Benzhydrylazetane-3-carbonitrile 8-oxa-1,3-diazaspiro[4.5]decane-2,4-dione (±)-amino(2-fluorophenyl)acetic acid 2-(2-Chlorophenyl)glycine AMINO-(3-CHLORO-PHENYL)-ACETIC ACID 2'-Fluoroacetophenone METHANOL-D1(OD) TERTIARY BUTANOL-D9 N-ETHYL-D5-AMINE HYDROCHLORIDE BENZOIC ACID-D CHLOROFORM-D TOLUENE-D3 Trans,trans muconic acid HC Blue-16 4-Amino-2-chloro-6,7-dimethoxyquinazoline Ethyl 4,5-bis(2-methoxyethoxy)-2-nitrobenzoate 2,3-Dimethoxypyridine 1-(3-Chlorophenyl)piperazine hydrochlorideRelated products of tetrahydrofuran
You may like
-
417721-36-9 4-Chloro-7-methoxyquinoline-6-carboxamide 98%View Details
417721-36-9 -
417721-36-9 95-99%View Details
417721-36-9 -
4-Chloro-7-Methoxyquinoline-6-Carboxamide 417721-36-9 98+View Details
417721-36-9 -
417721-36-9 4-Chloro-7-Methoxyquinoline-6-Carboxamide 98+View Details
417721-36-9 -
Product InrtroductionView Details -
DGO24View Details -
DGO29View Details -
DGO32View Details
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.