4-Chloro-2-phenylquinazoline
Synonym(s):AM-ex-OL;NSC 400965
- CAS NO.：6484-25-9
- Empirical Formula: C14H9ClN2
- Molecular Weight: 240.69
- MDL number: MFCD00006713
- EINECS: 229-346-2
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-09-12 18:53:49
What is 4-Chloro-2-phenylquinazoline?
Chemical properties
slightly yellow to yellow crystalline powder
The Uses of 4-Chloro-2-phenylquinazoline
4-Chloro-2-phenylquinazoline can be involved in the synthesis of biologically active molecules including: Nitrotriazole amines or nitroimidazole amines for use as antitrypanosomal activity and mammalian cytotoxicity.
The Uses of 4-Chloro-2-phenylquinazoline
Reactant involved in the synthesis of biologically active molecules including:
- Nitrotriazole amines or nitroimidazole amines for use as antitrypanosomal activity and mammalian cytotoxicity
- Quinazoline-containing piperazinylpyrimidine derivatives with antitumor activity
- Quinazoline substituted cyclopentane as HCV NS3/4A protease inhibitors
- Quinazolines with antibacterial and antitumor activity
- Aurora inhibitor MK-0457
Reactant involved in Suzuki-Miyaura cross-coupling and catalyst-free / base-free water promoted nucleophilic aromatic substitution
What are the applications of Application
4-Chloro-2-phenylquinazoline is a reactant involved in Suzuki-Miyaura cross-coupling
Synthesis Reference(s)
Journal of the American Chemical Society, 68, p. 1299, 1946 DOI: 10.1021/ja01211a055
Properties of 4-Chloro-2-phenylquinazoline
| Melting point: | 124-126 °C(lit.) |
| Boiling point: | 383.11°C (rough estimate) |
| Density | 1.285 |
| refractive index | 1.5749 (estimate) |
| storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C |
| pka | 0.67±0.30(Predicted) |
| form | Crystalline Powder |
| color | Slightly yellow to yellow |
| CAS DataBase Reference | 6484-25-9(CAS DataBase Reference) |
Safety information for 4-Chloro-2-phenylquinazoline
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 4-Chloro-2-phenylquinazoline
| InChIKey | OBHKONRNYCDRKM-UHFFFAOYSA-N |
New Products
5-bromo-4-fluoro-2-nitrobenzaldehyde (R)-(-)-2-Amino-1-propanol Cyclobutanone Fmoc-OSu 1-(2-Chloroethyl)pyrrolidine Hydrochloride 2-Amino-2-(4-methylphenyl)acetic acid β-Bromostyrene Ethyl 3-phenylpropanoate Phenethyl cinnamate Dipropyl disulfide 4 pentyn 1 ol N-Vinylformamide Methacrylate-PEG-Methacrylate, Mn:35000 2,4-Dihydroxyacetophenone 2-Chloro 5-Fluoro Pyridine Vasicinone 2-Chloroisonicotinic Acid Tween 80 or Polysorbate 80 2-Butyn-1-oL 2-Pentyn-1-oL 4-Nitrobenzotrifluoride N-(4-fluoro-2-methoxy-5-nitrophenyl)-4-(1-methyl-1H-indol-3-yl)pyrimidin-2-amine Pirtobrutinib intd. N-(4-Cyano-3-(trifluoromethyl)phenyl)-2-methyloxirane-2-carboxamideRelated products of tetrahydrofuran
You may like
-
Fmoc-OSu 98+View Details
82911-69-1 -
(R)-(-)-2-Amino-1-propanol 35320-23-1 98+View Details
35320-23-1 -
7250-67-1 1-(2-Chloroethyl)pyrrolidine Hydrochloride 98+View Details
7250-67-1 -
13227-01-5 98+View Details
13227-01-5 -
7250-67-1 1-(2-Chloroethyl)pyrrolidine Hydrochloride 98+View Details
7250-67-1 -
13227-01-5 98+View Details
13227-01-5 -
7250-67-1 1-(2-Chloroethyl)pyrrolidine Hydrochloride 98+View Details
7250-67-1 -
13227-01-5 98+View Details
13227-01-5
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.