4-(Benzyloxy)pyridine N-oxide

CAS NO.：2683-66-1
Empirical Formula: C12H11NO2
Molecular Weight: 201.22
MDL number: MFCD00047427
EINECS: 627-629-9
SAFETY DATA SHEET (SDS)
Update Date: 2026-05-28 02:45:38

What is 4-(Benzyloxy)pyridine N-oxide?

Chemical properties

White to off-white crystalline powder

The Uses of 4-(Benzyloxy)pyridine N-oxide

4-Benzyloxypyridine N-Oxide is an intermediate in the synthesis of 4-Hydroxy-1-methyl-2-pyridone (H947715), a reactant used in the synthesis of 3-deaza-3-halouracil nucleosides with cytostatic activity in three cancer cell lines.

General Description

4-(Benzyloxy)pyridine N-oxide is a 4-substituted pyridine-1-oxide. It undergoes hydrogenation over palladium to afford pyridine. It participates in the stereoselective synthesis of substituted pyridines, piperidines and piperazines.

Properties of 4-(Benzyloxy)pyridine N-oxide

Melting point:	178-179 °C (dec.)(lit.)
Boiling point:	415.3±20.0 °C(Predicted)
Density	1.09±0.1 g/cm3(Predicted)
pka	2.25±0.10(Predicted)
BRN	165005
CAS DataBase Reference	2683-66-1(CAS DataBase Reference)

Safety information for 4-(Benzyloxy)pyridine N-oxide

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up.