4-Aminophthalhydrazide
Synonym(s):6-Amino-2,3-dihydro-1,4-phthalazinedione;Isoluminol
- CAS NO.：3682-14-2
- Empirical Formula: C8H7N3O2
- Molecular Weight: 177.16
- MDL number: MFCD00010560
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-07-24 18:13:46
What is 4-Aminophthalhydrazide?
Chemical properties
Powder
The Uses of 4-Aminophthalhydrazide
4-Aminophthalhydrazide has been used in:
- chemiluminescence-based reactive oxygen species (ROS) assay in bone marrow (BM) neutrophils post-Yersinia pseudotuberculosis infection
- neutrophil ROS assays post-K. pneumonia exposure
- neutrophil ROS assays in response to formylated-methionine-leucine-proline
What are the applications of Application
4-Aminophthalhydrazide is a chemiluminescent molecule
Biochem/physiol Actions
4-Aminophthalhydrazide or isoluminol is a chemiluminescent compound that comprises a phthalazine ring. It is more hydrophilic than luminol. Isoluminol is commercially used in a wide variety of in vitro immunoassays and is a chemiluminescence amplifier for studying reactive oxygen species. It is also useful as an electroluminescence (ECL) biosensor and as a probe for rapid microbial detection.
Properties of 4-Aminophthalhydrazide
| Melting point: | 300 °C (lit.) |
| Density | 1.433±0.06 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| solubility | Soluble in ammonium hydroxide, sodium carbonate or other base. |
| form | Solid |
| pka | 10.78±0.20(Predicted) |
| color | White to Off-White |
| Sensitive | Air Sensitive |
| BRN | 164804 |
| CAS DataBase Reference | 3682-14-2(CAS DataBase Reference) |
Safety information for 4-Aminophthalhydrazide
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 4-Aminophthalhydrazide
| InChIKey | HUDPLKWXRLNSPC-UHFFFAOYSA-N |
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