4-AMINOPHENYL-1-PHENETHYLPIPERIDINE
Synonym(s):N-[1-(2-Phenylethyl)-4-piperidinyl]aniline;N-Phenyl-1-(2-phenylethyl)-4-piperidinamine;Despropionylfentanyl
- CAS NO.:21409-26-7
- Empirical Formula: C19H24N2
- Molecular Weight: 280.41
- MDL number: MFCD00179023
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:18:55
What is 4-AMINOPHENYL-1-PHENETHYLPIPERIDINE?
Description
4-ANPP (Item No. 18810) is an analytical reference material categorized as an opioid metabolite and a precursor in the synthesis of fentanyl (Item Nos. ISO60197 | 22659 | 14719) and other opioids. 4-ANPP is a metabolite of acetyl fentanyl (Item Nos. ISO60128 | ISO00128), butyryl fentanyl (Item Nos. 19734 | 14728), furanyl fentanyl (Item Nos. 19633 | 18705), acrylfentanyl (Item Nos. 23060 | 19312), and fentanyl. It has also been found as an impurity in illicit fentanyl preparations. 4-ANPP is regulated as a Schedule II compound in the United States. This product is intended for research and forensic applications.
Description
4-ANPP (CRM) (Item No. 22700) is a certified reference material that is categorized as a piperidinamine. It is an intermediate in the synthesis of fentanyl (Item Nos. 22659 | 14719 | ISO60197) from N-phenethyl-4-piperidone (NPP; ). As such, 4-ANPP has been used as a precursor for the manufacture of fentanyl and related opioids. 4-ANPP is also an impurity found in fentanyl preparations. It is a known metabolite of acetyl fentanyl (Item Nos. ISO00128 | ISO60128), butyryl fentanyl (Item Nos. 14728 | 19734), furanyl fentanyl (Item Nos. 18705 | 19633), acrylfentanyl , and fentanyl. 4-ANPP is regulated as a Schedule II compound in the United States. This product is intended for research and forensic applications.
Chemical properties
Pale Yellow Solid
The Uses of 4-AMINOPHENYL-1-PHENETHYLPIPERIDINE
A 3H-Fentanyl (F274990) metabolite
Properties of 4-AMINOPHENYL-1-PHENETHYLPIPERIDINE
| Melting point: | 94-96°C |
| Boiling point: | 172-176 °C(Press: 0.15 Torr) |
| Density | 1.075±0.06 g/cm3(Predicted) |
| Flash point: | 9°C |
| storage temp. | Hygroscopic, -20°C Freezer, Under Inert Atmosphere |
| form | Off-white solid. |
| pka | 9.03±0.10(Predicted) |
Safety information for 4-AMINOPHENYL-1-PHENETHYLPIPERIDINE
| Signal word | Danger |
| Pictogram(s) |
![]() Skull and Crossbones Acute Toxicity GHS06 |
| Precautionary Statement Codes |
P260:Do not breathe dust/fume/gas/mist/vapours/spray. P262:Do not get in eyes, on skin, or on clothing. P280:Wear protective gloves/protective clothing/eye protection/face protection. |
Computed Descriptors for 4-AMINOPHENYL-1-PHENETHYLPIPERIDINE
New Products
Cyclopropane-1,1-dicarboxylic acid Cefuroxime EP Impurity-A N-Nitroso hydroxy Cetrizine EP Impurity-A Noradrenaline EP Impurity D/Noradrenaline Methyl Ether Cetirizine EP Impurity A/Cetirizine CBHP Impurity Lantanoprost rc B Clidinium Bromide Impurity tert-Butyl (2S)-[1-amino-3-(4-iodophenyl)-1-oxopropan-2-yl]carbamate 4-amino-2-fluoro-N- methylbenzamide 5-Chloro-3- Methyl -1,3-2-benzoxazol-2(3H)-one N-(2-chloropyrimidin-4-yl)-N,2,3- trimethyl-2H- indazol 6-amine N-Boc-1,4-butanediamine 4-Bromo-2-fluoro-N-methylbenzamide valeronitrile 3-chlorobenzyl cyanide 3,4 Dimethoxy Benzylcyanide 3,4 Diethoxy Benzylcyanide 2-Chloro Benzylcyanide 3-Hydroxypropionitrile 5-azidovalericacid 6,6'-bis(difluoromethoxy)-2,2'-bis((3,4-dimethoxypyridin-2-yl)methylsulfinyl)-1H,1'H-5,5'-bibenzo[d]imidazole (1-((2'-(2-((1-((2'-(2H-tetrazol-5-yl)biphenyl-4-yl)methyl)-2-butyl-4-chloro-1H-imidazol-5-yl)methyl)-2H-tetrazol-5-yl)biphenyl-4-yl)methyl)-2-butyl-4-chloro-1H-imidazol-5-yl)methanol (1-((2'-(1-((1-((2'-(2H-tetrazol-5-yl)biphenyl-4-yl)methyl)-2-butyl-4-chloro-1H-imidazol-5-yl)methyl)-1H-tetrazol-5-yl)biphenyl-4-yl)methyl)-2-butyl-4-chloro-1H-imidazol-5-yl)methanol (4-Methoxyphenyl) hydrazine HydrochlorideRelated products of tetrahydrofuran


![N-(1-ACETYL-2,3-DIHYDRO-(1H)-INDOL-5-YL)-N-[1-(2-PHENYLETHYL)PIPERIDIN-4-YL]BENZAMIDE](https://img.chemicalbook.in/StructureFile/ChemBookStructure2/GIF/CB5112056.gif)


![N-(1-ACETYL-2,3-DIHYDRO-(1H)-INDOL-5-YL)-N-[1-(2-PHENYLETHYL)PIPERIDIN-4-YL]CYCLOPROPYLCARBOXAMIDE](https://img.chemicalbook.in/StructureFile/ChemBookStructure2/GIF/CB2116538.gif)
![4-PIPERIDINECARBOXYLIC ACID, 4-[(1-OXOPROPYL)PHENYLAMINO]](https://img.chemicalbook.in/CAS/GIF/186022-53-7.gif)
![4-PIPERIDINECARBOXYLIC ACID, 4-[(1-OXOPROPYL)PHENYLAMINO]-1-(2-PHENYLETHYL), METHYL ESTER ETHANEDIOATE](https://img.chemicalbook.in/StructureFile/ChemBookStructure4/GIF/CB7295706.gif)
You may like
-
4-Hydroxy-6-methyl-1-(4-methylphenyl)-2naphthalenecarboxylic acid 98+View Details
101894-09-1 -
83883-25-4 98+View Details
83883-25-4 -
54598-15-1 4,5,7-Trimethyl-2(1H)-quinolinone 98+View Details
54598-15-1 -
4-(6-HYDROXYHEXYLOXY)BENZOIC ACID 83883-25-4 98+View Details
83883-25-4 -
39973-47-2 NA 98+View Details
39973-47-2 -
2357109-89-6 98+View Details
2357109-89-6 -
39973-47-2 NA 98+View Details
39973-47-2 -
2357109-89-6 98+View Details
2357109-89-6

