4-Amino-6-chlorobenzene-1,3-disulfonamide
Synonym(s):3-Chloroaniline-4,6-disulfonamide;4-Amino-6-chloro-1,3-benzenedisulfonamide;4-Amino-6-chlorobenzene-1,3-disulfonamide
- CAS NO.：121-30-2
- Empirical Formula: C6H8ClN3O4S2
- Molecular Weight: 285.73
- MDL number: MFCD00007933
- EINECS: 204-463-1
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-07-04 14:24:19
What is 4-Amino-6-chlorobenzene-1,3-disulfonamide ?
Description
4-Amino-6-chlorobenzene-1,3-disulfonamide is obtained by treating the chloride with ammonia in tert-butanol and concentrating the solution by evaporation; the yield is 80 %. Condensation with formic acid gives 6-chloro-7-sulfamoyl-1,2,4-benzothiadiazine 1,1-dioxide, an important diuretic.
Chemical properties
Light Brown Solid
The Uses of 4-Amino-6-chlorobenzene-1,3-disulfonamide
Diuretic.
The Uses of 4-Amino-6-chlorobenzene-1,3-disulfonamide
4-Amino-6-chloro-1,3-benzenedisulfonamide was used in the synthesis of deuterated thiazides by undergoing condensation with appropriately labeled aldehydes.
What are the applications of Application
4-Amino-6-chloro-1,3-benzenedisulfonamide is an important target compound useful in long time detection of thiazide diuretics
Definition
ChEBI: Chloraminophenamide is a sulfonamide.
General Description
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Properties of 4-Amino-6-chlorobenzene-1,3-disulfonamide
| Melting point: | 257-261 °C(lit.) |
| Boiling point: | 614.4±65.0 °C(Predicted) |
| Density | 1.584 (estimate) |
| refractive index | 1.6100 (estimate) |
| storage temp. | 2-8°C |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| form | Powder |
| pka | 9.24±0.60(Predicted) |
| color | White to off-white |
| Merck | 14,2076 |
| BRN | 1083877 |
| CAS DataBase Reference | 121-30-2(CAS DataBase Reference) |
| EPA Substance Registry System | 1,3-Benzenedisulfonamide, 4-amino-6-chloro- (121-30-2) |
Safety information for 4-Amino-6-chlorobenzene-1,3-disulfonamide
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation |
| Precautionary Statement Codes |
P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection. |
Computed Descriptors for 4-Amino-6-chlorobenzene-1,3-disulfonamide
4-Amino-6-chlorobenzene-1,3-disulfonamide manufacturer
Clickchem Research LLP
2Y
Phone:+91-8140031133
Whatsapp: +91- 8140031133
product: 121-30-2 HYDROCHLOROTHIAZIDE EP IMPURITY B 90 % Above
Astrix Pharmaceuticals
1Y
Phone:+91-9989993941
Whatsapp: +91-9989993941
product: 4-Amino-6-chlorobenzene-1,3-disulphonamide 121-30-2 99.0%
Shubh Life Science
Gujarat
product: 4 Amino 6 Chloro 1 3 Benzene Disulfonamide, H2NC6H2(Cl)(SO2NH2)2, Grade: Commercial
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