4-Amino-3,5-dichlorophenacylbromide
- CAS NO.：37148-47-3
- Empirical Formula: C8H6BrCl2NO
- Molecular Weight: 282.95
- MDL number: MFCD09743795
- EINECS: 253-367-6
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-05-27 22:56:03
What is 4-Amino-3,5-dichlorophenacylbromide?
Chemical properties
Yellow Solid
The Uses of 4-Amino-3,5-dichlorophenacylbromide
1-(4-Amino-3,5-dichlorophenyl)-2-bromoethanone Hydrobromide is an intermediate in synthesizing Clenproperol-d7 (C573002). A labelled related drug of Clenbuterol (C569998), a β-agonist which can be used as a growth promoter in farm animals.
The Uses of 4-Amino-3,5-dichlorophenacylbromide
4-Amino-3,5-dichloro-alpha-bromoacetophenone is an impurity reference for Clenbuterol and can be used as a reference substance to analyze drug quality. It is widely used in organic synthesis and drug production.
Preparation
Dissolve 4-amino-3, 5-dichloroacetophenone in chloroform and heat to 65°C. Add bromine dropwise with stirring, stir for a few minutes after adding, then add ethanol and stir. Freeze, filter out the crystals, wash with chloroform, and dry at low temperature to obtain finished products.
Properties of 4-Amino-3,5-dichlorophenacylbromide
| Melting point: | 142-1450C |
| Boiling point: | 396.4±42.0 °C(Predicted) |
| Density | 1.764±0.06 g/cm3(Predicted) |
| storage temp. | -20°C Freezer, Under Inert Atmosphere |
| solubility | DMSO (Slightly), Ethyl Acetate (Slightly) |
| form | Solid |
| pka | -2.21±0.10(Predicted) |
| color | Off-White to Yellow |
| Stability: | Moisture Sensitive |
| InChI | InChI=1S/C8H6BrCl2NO/c9-3-7(13)4-1-5(10)8(12)6(11)2-4/h1-2H,3,12H2 |
| CAS DataBase Reference | 37148-47-3 |
Safety information for 4-Amino-3,5-dichlorophenacylbromide
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 4-Amino-3,5-dichlorophenacylbromide
| InChIKey | ATKJJUFAWYSFID-UHFFFAOYSA-N |
| SMILES | C(=O)(C1=CC(Cl)=C(N)C(Cl)=C1)CBr |
New Products
N-Carbethoxy-4-piperidone 1-Aminocyclopentane carbonitrile Tetrabutylammonium perchlorate N,O-Dimethylhydroxylamine hydrochloride (RS)-beta-Amino-beta-(4-bromophenyl)propionic acid 2-Amino-5-bromo-4-(trifluoromethyl)pyridine N-Vinylformamide 4 pentyn 1 ol Phenethyl cinnamate Dipropyl disulfide Ethyl 3-phenylpropanoate β-Bromostyrene Methacrylate-PEG-Methacrylate, Mn:35000 2,4-Dihydroxyacetophenone 2-Chloro 5-Fluoro Pyridine Vasicinone 2-Chloroisonicotinic Acid Tween 80 or Polysorbate 80 5-Bromo-1-Pentyne 1-(2-Methyl-5-nitrophenyl)guanidine Nitrate Methyl trans-4-Aminocyclohexanecarboxylate Hydrochloride N-(4-Cyano-3-(trifluoromethyl)phenyl)-2-methyloxirane-2-carboxamide 2-Pentyn-1-oL 4-NitrobenzotrifluorideRelated products of tetrahydrofuran
![1-(4-amino-3,5-dichlorophenyl)-2-[(1,1-dimethylethyl)amino]ethan-1-one hydrochloride](https://img.chemicalbook.in/CAS/GIF/37148-49-5.gif)
You may like
-
144-83-2 Sulfapyridine 98+View Details
144-83-2 -
29976-53-2 98+View Details
29976-53-2 -
2-Amino-5-bromo-4-(trifluoromethyl)pyridine 98+View Details
944401-56-3 -
(RS)-beta-Amino-beta-(4-bromophenyl)propionic acid 39773-47-2 98+View Details
39773-47-2 -
6638-79-5 N,O-Dimethylhydroxylamine hydrochloride 98+View Details
6638-79-5 -
674783-97-2 98+View Details
674783-97-2 -
1-Aminocyclopentane carbonitrile 98+View Details
49830-37-7 -
Tetrabutylammonium perchlorate 1923-70-2 98+View Details
1923-70-2
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.