4-(ACETYLAMINO)PHENYL]IMIDODISULFURYL DIFLUORIDE
Synonym(s):(4-Acetamidophenyl)(fluorosulfonyl)sulfamoyl fluoride;AISF
- CAS NO.：2172794-56-6
- Empirical Formula: C8H8F2N2O5S2
- Molecular Weight: 314.29
- MDL number: MFCD31625434
- Update Date: 2026-05-28 02:55:08
![4-(ACETYLAMINO)PHENYL]IMIDODISULFURYL DIFLUORIDE Structural](https://img.chemicalbook.in/CAS/20200611/GIF/2172794-56-6.gif)
What is 4-(ACETYLAMINO)PHENYL]IMIDODISULFURYL DIFLUORIDE?
The Uses of 4-(ACETYLAMINO)PHENYL]IMIDODISULFURYL DIFLUORIDE
4-(Acetylamino)phenyl]imidodisulfuryl difluoride (AISF) is a shelf-stable, crystalline reagent for synthesis of fluorosulfates and sulfamoyl fluorides via reaction with phenol and amine nucleophiles. A convenient alternative to the toxic sulfuryl fluoride gas traditionally required for installation of the valuable -SO2F functional group, the solid reagent AISF will find wide utility in preparation of synthetic precursors as well as chemical biology, polymer chemistry, cross-coupling, and deoxyfluorination applications. This product was introduced collaboratively with Pfizer and BioDuro.
Properties of 4-(ACETYLAMINO)PHENYL]IMIDODISULFURYL DIFLUORIDE
| Melting point: | 146-149°C |
| Density | 1.741±0.06 g/cm3(Predicted) |
| pka | 14.00±0.70(Predicted) |
| form | powder or crystals |
Safety information for 4-(ACETYLAMINO)PHENYL]IMIDODISULFURYL DIFLUORIDE
Computed Descriptors for 4-(ACETYLAMINO)PHENYL]IMIDODISULFURYL DIFLUORIDE
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