4-(Acetylamino)phenyl]imidodisulfuryl difluoride
Synonym(s):(4-Acetamidophenyl)(fluorosulfonyl)sulfamoyl fluoride;AISF
- CAS NO.：2172794-56-6
- Empirical Formula: C8H8F2N2O5S2
- Molecular Weight: 314.29
- MDL number: MFCD31625434
- Update Date: 2026-09-12 18:54:58
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What is 4-(Acetylamino)phenyl]imidodisulfuryl difluoride?
The Uses of 4-(Acetylamino)phenyl]imidodisulfuryl difluoride
4-(Acetylamino)phenyl]imidodisulfuryl difluoride (AISF) is a shelf-stable, crystalline reagent for synthesis of fluorosulfates and sulfamoyl fluorides via reaction with phenol and amine nucleophiles. A convenient alternative to the toxic sulfuryl fluoride gas traditionally required for installation of the valuable -SO2F functional group, the solid reagent AISF will find wide utility in preparation of synthetic precursors as well as chemical biology, polymer chemistry, cross-coupling, and deoxyfluorination applications. This product was introduced collaboratively with Pfizer and BioDuro.
Properties of 4-(Acetylamino)phenyl]imidodisulfuryl difluoride
| Melting point: | 146-149°C |
| Density | 1.741±0.06 g/cm3(Predicted) |
| pka | 14.00±0.70(Predicted) |
| form | powder or crystals |
Safety information for 4-(Acetylamino)phenyl]imidodisulfuryl difluoride
Computed Descriptors for 4-(Acetylamino)phenyl]imidodisulfuryl difluoride
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