4-(3,4-DICHLOROPHENYL)-5-(4-PYRIDINYL)-2-THIAZOLAMINE
- CAS NO.：252198-68-8
- Empirical Formula: C14H9Cl2N3S
- Molecular Weight: 322.21
- MDL number: MFCD08703116
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-05-04 17:34:36
What is 4-(3,4-DICHLOROPHENYL)-5-(4-PYRIDINYL)-2-THIAZOLAMINE?
Definition
ChEBI: CGH 2466 is a member of thiazoles.
Biological Activity
Adenosine A 1 , A 2B and A 3 receptor antagonist (IC 50 values are 19, 21, and 80 nM respectively). Also inhibits p38 MAPK (IC 50 = 187-400 nM) and phosphodiesterase type 4D (IC 50 = 22 nM). Displays potent anti-inflammatory effects in vitro and in vivo . Potentially useful for asthma and chronic obstructive pulmonary disease (COPD) research.
Properties of 4-(3,4-DICHLOROPHENYL)-5-(4-PYRIDINYL)-2-THIAZOLAMINE
| storage temp. | Desiccate at +4°C |
Safety information for 4-(3,4-DICHLOROPHENYL)-5-(4-PYRIDINYL)-2-THIAZOLAMINE
Computed Descriptors for 4-(3,4-DICHLOROPHENYL)-5-(4-PYRIDINYL)-2-THIAZOLAMINE
New Products
Indole Methyl Resin tert-butyl 9-methoxy-3-azaspiro[5.5]undecane-3-carboxylate 4-Chloro-7-tosy1-7Hpyrrolo[2,3-d]pyrimidine 2,5-dichloro-N-hydroxy-4,6-dimethylpyridine-3-carboximidamide 4-chloromethyl-5-methyl-1,3-dioxol-2-one (DMDO-Cl) 2,2-Dimethoxy-7-azaspiro[3.5]nonane hydrochloride 1-Boc-4-cyanopiperidine R-2-BENZYLOXY PROPIONIC ACID 1,1’-CARBONYLDIIMIDAZOLE 1,1’-CARBONYLDI (1,2-4 TRIAZOLE) Methyl 6-methylnicotinate TETRAHYDRO-2H-PYRAN-3-OL tert-Butyl carbazate 2-Methoxyphenothiazine N-methyl -4-piperidone 2-((4-morpholinophenylamino) (methylthio) methylene) malononitrile 2,4-dihydroxybenzaldehyde 3-(4-morpholinophenylamino)-5-amino-1H-pyrazole-4-carbonitrile Methyl 2-methylquinoline-6-carboxylate 2,6-dichloro-4-nitropyridine 4-Bromo-2-chlorobenzonitrile 1-methylindoline-2,3-dione methyl 4-ethyl-3-ethynylbenzoate Methyl phenyl sulfoneRelated products of tetrahydrofuran
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