Rink Amide Linker
Synonym(s):Rink amide linker
- CAS NO.：145069-56-3
- Empirical Formula: C32H29NO7
- Molecular Weight: 539.58
- MDL number: MFCD00153509
- EINECS: 604-455-1
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:16:38
What is Rink Amide Linker?
The Uses of Rink Amide Linker
Rink amide linker (CAS# 145069-56-3) is a selective aldose reductase inhibitor and a potential antidiabetic drug.
What are the applications of Application
Most linkers are bifunctional spacers, with one end permanently anchoring to the resin and the other end temporarily linking to the peptide. Peptides anchoring to Rink linker can be easily cleaved under acidic conditions. Since the discovery of Rink linker, it has been grafted to a variety of resins and widely used for scientific investigations and industrial solid-phase peptide synthesis. Thus, Rink Amide Linker is the key reagent to prepare this series of Rink-resins[1].
Origin
Rink Amide Linker was first designed by Rink and further developed by Bernatowicz and co-workers for the preparation of peptide C-terminal amides[1]. Rink Amide Linker is also known as commercial Knorr linker.
References
[1] Qin L, et al. An improved and practical synthesis of Fmoc Rink linker. Journal of Chemical Research, 2019.
Properties of Rink Amide Linker
| Melting point: | ~180 °C (dec.) |
| storage temp. | 2-8°C |
| solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. |
| form | Powder |
| BRN | 5841553 |
| CAS DataBase Reference | 145069-56-3(CAS DataBase Reference) |
Safety information for Rink Amide Linker
Computed Descriptors for Rink Amide Linker
| InChIKey | UPMGJEMWPQOACJ-UHFFFAOYSA-N |
| SMILES | C(O)(=O)COC1=CC=C(C(C2=CC=C(OC)C=C2OC)NC(OCC2C3C(=CC=CC=3)C3C2=CC=CC=3)=O)C=C1 |
New Products
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