3(S)-Oxidosqualene

Synonym(s):(S)-2,3-Epoxy-2,3-dihydrosqualene;(S)-22,23-Epoxy-2,6,10,15,19,23-hexamethyl-2,6,10,14,18-tetracosapentaene;(S)-Squalene 2,3-epoxide;(S)-Squalene 2,3-oxide

CAS NO.：54910-48-4
Empirical Formula: C30H50O
Molecular Weight: 426.72
MDL number: MFCD28100799
Update Date: 2026-01-13 11:21:08

What is 3(S)-Oxidosqualene?

The Uses of 3(S)-Oxidosqualene

3(S)-Oxidosqualene is used in the synthesis of lanosterol, a precursor to cholesterol.

Definition

ChEBI: (S)-2,3-epoxysqualene is a 2,3-epoxysqualene in which the chiral centre has S configuration. It is converted into lanosterol by lanosterol synthase (EC 5.4.99.7) in a key rate-limiting step in the biosynthesis of chloesterol, steroid hormones, and vitamin D. It has a role as a human metabolite, a Saccharomyces cerevisiae metabolite and a mouse metabolite. It derives from a hydride of a squalene.

Biochem/physiol Actions

(S)-2,3-Epoxysqualene is an intermediate of many metabolic pathways such as the steroid biosynthesis, sesquiterpenoid and triterpenoid biosynthesis, biosynthesis of plant secondary metabolites, biosynthesis of terpenoids and steroids, biosynthesis of plant hormones, biosynthesis of secondary metabolites, and biosynthesis of antibiotics.

Properties of 3(S)-Oxidosqualene

Boiling point:	164-165 °C(Press: 10 Torr)
Density	0.882±0.06 g/cm3(Predicted)
storage temp.	-20°C
solubility	Chloroform (Slightly), Methanol (Slightly)
form	Oil
color	Colourless

Safety information for 3(S)-Oxidosqualene

Computed Descriptors for 3(S)-Oxidosqualene

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