3,4-DIHYDROISOQUINOLINE
- CAS NO.：3230-65-7
- Empirical Formula: C9H9N
- Molecular Weight: 131.17
- MDL number: MFCD00033714
- EINECS: 221-769-0
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-05-28 03:50:41
What is 3,4-DIHYDROISOQUINOLINE?
The Uses of 3,4-DIHYDROISOQUINOLINE
3,4-Dihydroisoquinoline is derived from 1,2,3,4-Tetrahydroisoquinoline (T293820), which is used as a reagent in the preparation of 4-(1,2,4-oxadiazol-5-yl)piperidine-1-carboxamides as antiproliferative tubulin inhibitors.
The Uses of 3,4-DIHYDROISOQUINOLINE
3,4-Dihydroisoquinoline can be used as a reactant to synthesize:
- 5,6-Dihydro-8H-isoquino[1,2-b]quinazolin-8-one by decarboxylative cyclization reaction with isatoic anhydride using tetrabutylammonium iodide (TBAI).
- 1-naphtholyl tetrahydroisoquinoline by aza-Friedel-Crafts reaction with various naphthols.
- 3,4-dihydroisoquinoline pseudo bases, which are employed as starting materials for the preperation of 3-benzazepine derivatives.
Synthesis Reference(s)
Tetrahedron Letters, 35, p. 6567, 1994 DOI: 10.1016/S0040-4039(00)78274-8
Properties of 3,4-DIHYDROISOQUINOLINE
| Melting point: | 251-254℃ |
| Boiling point: | 241.8±20.0℃ (760 Torr) |
| Density | 1.05±0.1 g/cm3 (20 ºC 760 Torr) |
| refractive index | 1.6041 (589.3 nm 30℃) |
| Flash point: | 91.6±22.6℃ |
| storage temp. | 2-8°C |
| pka | 5.80±0.20(Predicted) |
Safety information for 3,4-DIHYDROISOQUINOLINE
| Signal word | Danger |
| Pictogram(s) |
 Skull and Crossbones Acute Toxicity GHS06 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H310:Acute toxicity,dermal H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation |
| Precautionary Statement Codes |
P262:Do not get in eyes, on skin, or on clothing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 3,4-DIHYDROISOQUINOLINE
New Products
N-Carbethoxy-4-piperidone 1-Aminocyclopentane carbonitrile Tetrabutylammonium perchlorate N,O-Dimethylhydroxylamine hydrochloride (RS)-beta-Amino-beta-(4-bromophenyl)propionic acid 2-Amino-5-bromo-4-(trifluoromethyl)pyridine N-Vinylformamide 4 pentyn 1 ol Phenethyl cinnamate Dipropyl disulfide Ethyl 3-phenylpropanoate β-Bromostyrene Methacrylate-PEG-Methacrylate, Mn:35000 2,4-Dihydroxyacetophenone 2-Chloro 5-Fluoro Pyridine Vasicinone 2-Chloroisonicotinic Acid Tween 80 or Polysorbate 80 5-Bromo-1-Pentyne 1-(2-Methyl-5-nitrophenyl)guanidine Nitrate Methyl trans-4-Aminocyclohexanecarboxylate Hydrochloride N-(4-Cyano-3-(trifluoromethyl)phenyl)-2-methyloxirane-2-carboxamide 2-Pentyn-1-oL 4-NitrobenzotrifluorideRelated products of tetrahydrofuran
You may like
-
3,4-Dihydroisoquinoline CAS 3230-65-7View Details
3230-65-7 -
144-83-2 Sulfapyridine 98+View Details
144-83-2 -
29976-53-2 98+View Details
29976-53-2 -
(RS)-beta-Amino-beta-(4-bromophenyl)propionic acid 39773-47-2 98+View Details
39773-47-2 -
6638-79-5 N,O-Dimethylhydroxylamine hydrochloride 98+View Details
6638-79-5 -
674783-97-2 98+View Details
674783-97-2 -
1-Aminocyclopentane carbonitrile 98+View Details
49830-37-7 -
Tetrabutylammonium perchlorate 1923-70-2 98+View Details
1923-70-2
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.