3,3′-[6,6′-bi-1H-Benzimidazole]-2,2′-diylbis-benzenamine
Synonym(s):3,3′-[6,6′-bi-1H-Benzimidazole]-2,2′-diylbis-benzenamine
- CAS NO.：4402-18-0
- Empirical Formula: C26H20N6
- Molecular Weight: 416.48
- MDL number: MFCD01137750
- Update Date: 2025-12-15 16:23:17
![3,3′-[6,6′-bi-1H-Benzimidazole]-2,2′-diylbis-benzenamine Structural](https://img.chemicalbook.in/CAS/20180906/GIF/4402-18-0.gif)
What is 3,3′-[6,6′-bi-1H-Benzimidazole]-2,2′-diylbis-benzenamine?
Biochem/physiol Actions
DDRI-18 (DNA Damage Response Inhibitor-18) inhibits nonhomologous end-joining (NHEJ) DNA repair following double strand DNA breaks induced by ionizing radiation, and enhances the effects of DNA-damaging cancer drugs like etoposide, camptothecin and doxorubicin.
Properties of 3,3′-[6,6′-bi-1H-Benzimidazole]-2,2′-diylbis-benzenamine
| Melting point: | 297-299 °C |
| Boiling point: | 835.8±75.0 °C(Predicted) |
| Density | 1.382±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | DMSO: soluble10mg/mL |
| form | powder |
| pka | 10.77±0.10(Predicted) |
| color | white to beige |
Safety information for 3,3′-[6,6′-bi-1H-Benzimidazole]-2,2′-diylbis-benzenamine
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation H413:Hazardous to the aquatic environment, long-term hazard |
| Precautionary Statement Codes |
P273:Avoid release to the environment. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 3,3′-[6,6′-bi-1H-Benzimidazole]-2,2′-diylbis-benzenamine
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