3,20-Dioxopregn-4-en-17-beta-yl acetate
- CAS NO.：17308-02-0
- Empirical Formula: C23H32O4
- Molecular Weight: 372.51
- MDL number: MFCD00021156
- EINECS: 241-337-5
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-10-23 17:25:30
What is 3,20-Dioxopregn-4-en-17-beta-yl acetate?
The Uses of 3,20-Dioxopregn-4-en-17-beta-yl acetate
3,20-Dioxopregn-4-en-17-beta-yl acetate, also known as 17-Hydroxyprogesterone acetate, is a new steroid for oral administration. It has a progestational activity which is at least twice that of anhydrohydroxyprogesterone[1].
Mechanism of action
3,20-Dioxopregn-4-en-17-beta-yl acetate could induces secretory changes in the endometrium and luteal changes in the exfoliated vaginal epithelial cells, reduces fern-like patterns of the cervical mucus, causes a rise of basal body temperature, and induces withdrawal bleeding in castrates[1].
References
[1] Davis M, et al. 17-α-HYDROXYPROGESTERONE ACETATE; AN EFFECTIVE PROGESTATIONAL SUBSTANCE ON ORAL ADMINISTRATION. The Journal of clinical endocrinology and metabolism, 1957; 17: 1237–1244,.
Properties of 3,20-Dioxopregn-4-en-17-beta-yl acetate
| Melting point: | 198 °C |
| Boiling point: | 490.2±45.0 °C(Predicted) |
| Density | 1.14±0.1 g/cm3(Predicted) |
| InChI | InChI=1/C23H32O4/c1-14(24)23(27-15(2)25)12-9-20-18-6-5-16-13-17(26)7-10-21(16,3)19(18)8-11-22(20,23)4/h13,18-20H,5-12H2,1-4H3/t18-,19+,20+,21+,22+,23-/s3 |
| CAS DataBase Reference | 17308-02-0(CAS DataBase Reference) |
Safety information for 3,20-Dioxopregn-4-en-17-beta-yl acetate
Computed Descriptors for 3,20-Dioxopregn-4-en-17-beta-yl acetate
| InChIKey | VTHUYJIXSMGYOQ-NCZDLRRGNA-N |
| SMILES | O([C@]1(CC[C@@]2([H])[C@]3([H])CCC4=CC(=O)CC[C@]4(C)[C@@]3([H])CC[C@]12C)C(=O)C)C(=O)C |&1:1,4,6,16,18,22,r| |
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