3-(Trifluoromethyl)pyridine-2-carboxylic acid
Synonym(s):3-(Trifluoromethyl)-2-picolinic acid
- CAS NO.：87407-12-3
- Empirical Formula: C7H4F3NO2
- Molecular Weight: 191.11
- MDL number: MFCD07375386
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-07-14 15:28:00
What is 3-(Trifluoromethyl)pyridine-2-carboxylic acid?
The Uses of 3-(Trifluoromethyl)pyridine-2-carboxylic acid
As Picolinic acid (P437220) derivative, 3-(Trifluoromethyl)pyridine-2-carboxylic acid can be used in the synthesis of oxazine derivatives that act as BACE inhibitors for treatment of diabetes and neurological disorders.
The Uses of 3-(Trifluoromethyl)pyridine-2-carboxylic acid
Picolinic acid (P437220) derivative used in the synthesis of oxazine derivatives that act as BACE inhibitors for treatment of diabetes and neurological disorders.
Synthesis Reference(s)
Tetrahedron, 50, p. 12259, 1994 DOI: 10.1016/S0040-4020(01)89575-2
Properties of 3-(Trifluoromethyl)pyridine-2-carboxylic acid
| Melting point: | 125-130°C |
| Boiling point: | 274.4±40.0 °C(Predicted) |
| Density | 1.484±0.06 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| form | Solid |
| pka | 2.67±0.36(Predicted) |
| color | Off-White |
Safety information for 3-(Trifluoromethyl)pyridine-2-carboxylic acid
| Signal word | Danger |
| Pictogram(s) |
 Skull and Crossbones Acute Toxicity GHS06 |
| GHS Hazard Statements |
H301:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 3-(Trifluoromethyl)pyridine-2-carboxylic acid
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