3'-Methylacetanilide

Synonym(s):m-Acetotoluidide

CAS NO.：537-92-8
Empirical Formula: C9H11NO
Molecular Weight: 149.19
MDL number: MFCD00014962
EINECS: 208-678-1
SAFETY DATA SHEET (SDS)
Update Date: 2026-01-13 13:16:54

What is 3'-Methylacetanilide?

Chemical properties

white crystalline solid

General Description

White solid.

Air & Water Reactions

Water insoluble.

Reactivity Profile

3'-Methylacetanilide is an amide. Flammable gases are formed by the reaction of organic amides with strong reducing agents. Amides are very weak bases (weaker than water). Imides are less basic yet and in fact react with strong bases to form salts. That is, they can react as acids. Mixing amides with dehydrating agents such as P2O5 or SOCl2 generates the corresponding nitrile. The combustion of these compounds generates mixed oxides of nitrogen (NOx).

Health Hazard

ACUTE/CHRONIC HAZARDS: When heated to decomposition 3'-Methylacetanilide emits toxic fumes of nitrogen oxides.

Fire Hazard

Flash point data for 3'-Methylacetanilide are not available; however, 3'-Methylacetanilide is probably combustible.

Safety Profile

Moderately toxic by ingestion. Seealso p-ACETOTOLUIDIDE. When heated todecomposition it emits toxic fumes of NOx.

Purification Methods

Crystallise the toluidide from H2O, EtOH, aqueous EtOH or Et2O/pet ether (m 66o). UV: max 245nm (EtOH). [Beilstein 12 H 860, 12 I 400, 12 II 468, 12 III 1962, 12 IV 1823.]

Properties of 3'-Methylacetanilide

Melting point:	65-67 °C (lit.)
Boiling point:	303 °C (lit.)
Density	1.1410
vapor pressure	16 mm Hg ( 163 °C)
refractive index	1.5279 (estimate)
storage temp.	Inert atmosphere,Room Temperature
solubility	alcohol: freely soluble(lit.)
form	powder to crystal
pka	15.12±0.70(Predicted)
color	White to Light gray to Light yellow
Merck	14,74
Stability:	Stable. Incompatible with strong oxidizing agents.
CAS DataBase Reference	537-92-8(CAS DataBase Reference)
NIST Chemistry Reference	N-(3-Tolyl)acetic acid amide(537-92-8)
EPA Substance Registry System	m-Acetotoluidide (537-92-8)

Safety information for 3'-Methylacetanilide

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P280:Wear protective gloves/protective clothing/eye protection/face protection. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P501:Dispose of contents/container to..…