3-Methoxybenzamide

Synonym(s):m-Anisamide

CAS NO.：5813-86-5
Empirical Formula: C8H9NO2
Molecular Weight: 151.16
MDL number: MFCD00007986
EINECS: 227-379-7
SAFETY DATA SHEET (SDS)
Update Date: 2025-12-16 16:15:04

What is 3-Methoxybenzamide?

The Uses of 3-Methoxybenzamide

3-Methoxybenzamide is act as an inhibitor of ADP-ribosyltransferase. It is also a weak inhibitor of the essential bacterial cell division protein FtsZ. Alkyl derivatives of 3-Methoxybenzamide are potent antistaphylococcal compounds with suboptimal drug-like properties.

What are the applications of Application

3-Methoxybenzamide is an inhibitor of ART (ADP-ribosyltransferase

Biological Activity

3-Methoxybenzamide (3-MBA), an inhibitor of ADP-ribosyltransferase (ADPRTs) and PARP, inhibits cell division in Bacillus subtilis, leading to filamentation and eventually lysis of cells. 3-Methoxybenzamide (3-MBA) enhances in vitro plant growth, microtuberization, and transformation efficiency of blue potato (Solanum tuberosum L. subsp. andigenum).

in vitro

3-Methoxybenzamide (0-30 mM) affects septation via the FtsZ system during both vegetative growth and sporulation. 3-Methoxybenzamide (3 MB; 0.2 to 0.6 mM) significantly increaseS the growth and microtuber formation of in vitro propagated plants.

Properties of 3-Methoxybenzamide

Melting point:	132.5-135.5 °C (lit.)
Boiling point:	280.0±23.0 °C(Predicted)
Density	1.143±0.06 g/cm3(Predicted)
storage temp.	Sealed in dry,Room Temperature
solubility	DMF: 30 mg/ml,DMSO: 30 mg/ml,DMSO:PBS (pH 7.2) (1:1): 0.50 mg/ml,Ethanol: 1 mg/ml
pka	15.81±0.50(Predicted)
form	A crystalline solid
color	White to off-white
Water Solubility	Soluble in water.
BRN	2206857
InChI	InChI=1S/C8H9NO2/c1-11-7-4-2-3-6(5-7)8(9)10/h2-5H,1H3,(H2,9,10)
CAS DataBase Reference	5813-86-5(CAS DataBase Reference)

Safety information for 3-Methoxybenzamide

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up.