3-Hydroxyphthalic anhydride
- CAS NO.：37418-88-5
- Empirical Formula: C8H4O4
- Molecular Weight: 164.12
- MDL number: MFCD00011557
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-03-13 23:13:44
What is 3-Hydroxyphthalic anhydride?
Chemical properties
Beige powder
The Uses of 3-Hydroxyphthalic anhydride
3-Hydroxyphthalic Anhydride is used to synthesize 3-Hydroxyphthalic Anhydride-modified human serum albumin whichhas high potency as a microbicide for prevention of the sexual transmission of HIV. It is also used as a reagent in organicsynthesis of other compounds including that of inhibitors of NF-κB derived from thalidomide.
Synthesis Reference(s)
Journal of the American Chemical Society, 77, p. 5092, 1955 DOI: 10.1021/ja01624a042
Synthesis, p. 788, 1985 DOI: 10.1055/s-1985-31350
Properties of 3-Hydroxyphthalic anhydride
| Melting point: | 199-202 °C (lit.) |
| Boiling point: | 365.4±25.0 °C(Predicted) |
| Density | 1.624±0.06 g/cm3(Predicted) |
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | Acetonitrile (Slightly), DMSO (Slightly) |
| form | Powder |
| pka | 6.25±0.20(Predicted) |
| color | White to beige |
| BRN | 135783 |
| Stability: | Hygroscopic |
| CAS DataBase Reference | 37418-88-5(CAS DataBase Reference) |
Safety information for 3-Hydroxyphthalic anhydride
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 3-Hydroxyphthalic anhydride
| InChIKey | CCTOEAMRIIXGDJ-UHFFFAOYSA-N |
New Products
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