3-FORMYL-6-METHYLCHROMONE

Synonym(s):6-Methyl-4-oxo-4H-1-benzopyran-3-carboxaldehyde

CAS NO.：42059-81-4
Empirical Formula: C11H8O3
Molecular Weight: 188.18
MDL number: MFCD00138943
SAFETY DATA SHEET (SDS)
Update Date: 2025-07-14 15:27:00

What is 3-FORMYL-6-METHYLCHROMONE?

Chemical properties

yellow powder

The Uses of 3-FORMYL-6-METHYLCHROMONE

3-Formyl-6-methylchromone may be used in the preparation of series of Schiff′s bases, via reaction with aromatic sulfonamides, such as sulfanilamide, homosulfanilamide, 4-aminoethyl-benzenesulfonamide, a pyrimidinyl-substituted sulfanilamide derivative, sulfaguanidine and 4-amino-6-trifluoromethyl-benzene-1,3-disulfonamide. It may be used in the preparation of Schiff base, which undergoes addition reaction with diethyl phosphite to afford bis[(1,2,4,3-triazaphospholyl)(chromonyl)aminomethylphosphonate] derivative and bis[(1,2,4,3-triazaphospholyl)(chromonyl)phosphorylamino-methylphosphonate] derivative.

General Description

3-Formyl-6-methylchromone is a 3-formyl-substituted chromone. The combustion calorimetric estimation of the enthalpy of combustion of 3-formyl-6-methylchromone has been reported. Its anti-proliferative action on the MDR human colon cancer and mouse lymphoma has been investigated.

Properties of 3-FORMYL-6-METHYLCHROMONE

Melting point:	172-173 °C (lit.)
Boiling point:	335.1±42.0 °C(Predicted)
Density	1.47 g/cm3
storage temp.	Inert atmosphere,Room Temperature
form	powder to crystal
color	White to Yellow to Green
λmax	308nm(Dioxane)(lit.)
CAS DataBase Reference	42059-81-4(CAS DataBase Reference)

Safety information for 3-FORMYL-6-METHYLCHROMONE

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation
Precautionary Statement Codes	P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection.