3-Fluoro-4-methoxyphenylacetic acid
Synonym(s):3-Fluoro-4-methoxyphenylacetic acid
- CAS NO.：452-14-2
- Empirical Formula: C9H9FO3
- Molecular Weight: 184.16
- MDL number: MFCD00060353
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-05-27 17:22:49
What is 3-Fluoro-4-methoxyphenylacetic acid ?
Synthesis
3-fluoro-4-methoxyphenylacetonitrile (42 g, 0.25 mol) was heated for 5 h with 32 g of potassium hydroxide solution in 120 mL of ethanol and 30 mL of water. After the distillation of ethanol, the residue was diluted with water to a volume of 175 mL. The solution was filtered over the charcoal, and the filtrate was acidified by 50 percent H2SO4. The resulting solid was filtered and dried, yielding 3-Fluoro-4-methoxyphenylacetic acid.
Properties of 3-Fluoro-4-methoxyphenylacetic acid
| Melting point: | 111-113°C |
| Boiling point: | 309.0±27.0 °C(Predicted) |
| Density | 1.269±0.06 g/cm3(Predicted) |
| storage temp. | Store below +30°C. |
| pka | 4.25±0.10(Predicted) |
| color | White to off-white |
| CAS DataBase Reference | 452-14-2(CAS DataBase Reference) |
Safety information for 3-Fluoro-4-methoxyphenylacetic acid
| Signal word | Danger |
| Pictogram(s) |
 Corrosion Corrosives GHS05 |
| GHS Hazard Statements |
H318:Serious eye damage/eye irritation |
| Precautionary Statement Codes |
P280:Wear protective gloves/protective clothing/eye protection/face protection. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 3-Fluoro-4-methoxyphenylacetic acid
New Products
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