3-Ethyl-4-methyl-3-pyrrolin-2-one
- CAS NO.：766-36-9
- Empirical Formula: C7H11NO
- Molecular Weight: 125.17
- MDL number: MFCD00173861
- EINECS: 616-364-4
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-07-14 15:28:00
What is 3-Ethyl-4-methyl-3-pyrrolin-2-one?
The Uses of 3-Ethyl-4-methyl-3-pyrrolin-2-one
3-Ethyl-4-methyl-3-pyrrolin-2-one is used as an intermediate for the manufacture of medicines. It is used for the preparation of Glimepiride (G410150), and its intermediates and as antidiabetic agents.
What are the applications of Application
3-Ethyl-4-methyl-3-pyrrolin-2-one is a heterocyclic building block
General Description
3-Ethyl-4-methyl-3-pyrrolin-2-one, a five-membered α,β-unsaturated lactam derivative, has various applications in medicinal chemistry. It can be synthesized by employing following as starting materials:
- allylamine, via palladium(II)-assisted cyclization
- 4-methoxybenzylamine, via a ring-closing-metathesis strategy
- 3-ethyl-1-(4-methoxybenzyl)-4-methyl-1,5-dihydro-2H-pyrrol-2- one
Properties of 3-Ethyl-4-methyl-3-pyrrolin-2-one
| Melting point: | 100-104 °C (lit.) |
| Boiling point: | 279.0±23.0 °C(Predicted) |
| Density | 0.977±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | Chloroform (Slightly), Methanol (Slightly) |
| pka | 14.44±0.60(Predicted) |
| form | powder to crystal |
| color | White to Almost white |
| Water Solubility | Slightly soluble in water. |
| CAS DataBase Reference | 766-36-9(CAS DataBase Reference) |
Safety information for 3-Ethyl-4-methyl-3-pyrrolin-2-one
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation |
| Precautionary Statement Codes |
P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection. |
Computed Descriptors for 3-Ethyl-4-methyl-3-pyrrolin-2-one
3-Ethyl-4-methyl-3-pyrrolin-2-one manufacturer
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