3-Cyano-N-(1,3-diphenyl-1H-pyrazol-5-yl)benzamide
Synonym(s):3- Cyano-N-(1,3- di phenyl-1H- pyrazol-5-yl) benzamide;3-Cyano-N-(1,3-diphenyl-1H-pyrazol-5-yl)benzamide;3-Cyano-N-1,3-diphenyl-1H-pyrazol-5-yl)benzamide;mGluR5 Ligand, CDPPB - CAS 781652-57-1 - Calbiochem
- CAS NO.：781652-57-1
- Empirical Formula: C23H16N4O
- Molecular Weight: 364.4
- MDL number: MFCD12828752
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-05-28 01:05:06
What is 3-Cyano-N-(1,3-diphenyl-1H-pyrazol-5-yl)benzamide?
The Uses of 3-Cyano-N-(1,3-diphenyl-1H-pyrazol-5-yl)benzamide
3-Cyano-N-(1,3-diphenyl-1H-pyrazol-5-yl)benzamide is a glutamate metabotropic (mGluR5) positive allosteric modulator, used in the treatment of Phelan-McDermid syndrome caused by 22qI3 deletion. Studies have shown that 3-Cyano-N-(1,3-diphenyl-1H-pyrazol-5-yl)benzamide suppresses the incre ase of LDH release and caspase-3 activation induced by traumatic neuronal injury.
The Uses of 3-Cyano-N-(1,3-diphenyl-1H-pyrazol-5-yl)benzamide
CDPPB may be used in mGluR5-mediated cell signaling studies.
What are the applications of Application
mGluR5 Ligand, CDPPB is a selective, reversible, positive allosteric modulator for mGluR-5
Biochem/physiol Actions
CDPPB is a glutamate metabotropic mGluR5 positive allosteric modulator.
Storage
+4°C
Properties of 3-Cyano-N-(1,3-diphenyl-1H-pyrazol-5-yl)benzamide
| Melting point: | 210-212°C |
| storage temp. | 2-8°C |
| solubility | DMSO: ≥5mg/mL at warmed to 60°C |
| form | powder |
| color | white to beige |
Safety information for 3-Cyano-N-(1,3-diphenyl-1H-pyrazol-5-yl)benzamide
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 3-Cyano-N-(1,3-diphenyl-1H-pyrazol-5-yl)benzamide
New Products
9-Mesityl-10-methylacridinium perchlorate Sulfapyridine Fmoc-OSu (R)-(-)-2-Amino-1-propanol Cyclobutanone 5-bromo-4-fluoro-2-nitrobenzaldehyde 4 pentyn 1 ol N-Vinylformamide Phenethyl cinnamate Pyrrolo[1,2-a]pyrimidine-6-carboxylic acid, 4,6,7,8-tetrahydro-4-oxo-, sodium salt (1:1), (6S) Ethyl 3-phenylpropanoate β-Bromostyrene Methacrylate-PEG-Methacrylate, Mn:35000 2,4-Dihydroxyacetophenone 2-Chloro 5-Fluoro Pyridine Vasicinone 2-Chloroisonicotinic Acid Tween 80 or Polysorbate 80 Methyl trans-4-Aminocyclohexanecarboxylate Hydrochloride N-(4-fluoro-2-methoxy-5-nitrophenyl)-4-(1-methyl-1H-indol-3-yl)pyrimidin-2-amine Pirtobrutinib intd. 4-Nitrobenzotrifluoride 2-Pentyn-1-oL N-(4-Cyano-3-(trifluoromethyl)phenyl)-2-methyloxirane-2-carboxamideRelated products of tetrahydrofuran
You may like
-
CDPPB CAS 781652-57-1View Details
781652-57-1 -
1191-95-3 Cyclobutanone 98+View Details
1191-95-3 -
Fmoc-OSu 98+View Details
82911-69-1 -
(R)-(-)-2-Amino-1-propanol 35320-23-1 98+View Details
35320-23-1 -
1191-95-3 Cyclobutanone 98+View Details
1191-95-3 -
213382-45-7 98+View Details
213382-45-7 -
Fmoc-OSu 98+View Details
82911-69-1 -
(R)-(-)-2-Amino-1-propanol 35320-23-1 98+View Details
35320-23-1
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.