3-CYANO-7-ETHOXYCOUMARIN
- CAS NO.：117620-77-6
- Empirical Formula: C12H9NO3
- Molecular Weight: 215.2
- MDL number: MFCD00467359
- EINECS: 200-562-0
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-05-11 16:31:51
What is 3-CYANO-7-ETHOXYCOUMARIN?
The Uses of 3-CYANO-7-ETHOXYCOUMARIN
3-Cyano-7-ethoxycoumarin has been used as a substrate in cytochrome P (CYP) inhibition for fluorescence measurement.
The Uses of 3-CYANO-7-ETHOXYCOUMARIN
Substrate for determination of cytochrom P-450 dependent oxidases; about 50-100 times more sensitive than conventional substrate ethoxy-resorufin due to higher turn over rate.
What are the applications of Application
7-Ethoxycoumarin-3-carbonitrile is a fluorescent probe
General Description
3-Cyano-7-ethoxycoumarin is a fluorescent substrate for Cytochrome P450 1A1 (CYP1A1), Cytochrome P450 1A2 (CYP1A2), Cytochrome P450 2C9 (CYP2C9) and Cytochrome P450 2C19 (CYP2C19).
Biochem/physiol Actions
Fluorescent probe useful in microsomal dealkylase studies. Typical drug-drug interactions resulting from enzyme inhibition.
Properties of 3-CYANO-7-ETHOXYCOUMARIN
| Melting point: | 210-212°C |
| Boiling point: | 396.8±42.0 °C(Predicted) |
| Density | 1.29±0.1 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | DMSO: soluble |
| form | Solid |
| color | yellow to orange |
| λmax | 356 nm (Buffer pH7); 355 nm(MeOH) |
| Biological Applications | As a substrate for
measuring cytochrome P450 enzymes activity;
cytochrome P450 inhibition assays;
drug design;
drug metabolism;
treating viral or parasite
infections. |
Safety information for 3-CYANO-7-ETHOXYCOUMARIN
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 3-CYANO-7-ETHOXYCOUMARIN
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