3-Chloro-4-fluorophenylboronic acid
Synonym(s):(3-Chloro-4-fluorophenyl-1-yl)boronic acid;3-Chloro-4-fluorobenzeneboronic acid;4-Fluoro-3-chlorophenylboronic acid
- CAS NO.:144432-85-9
- Empirical Formula: C6H5BClFO2
- Molecular Weight: 174.37
- MDL number: MFCD00051800
- EINECS: 675-657-5
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-04-24 14:58:18
What is 3-Chloro-4-fluorophenylboronic acid?
Chemical properties
Off-white to faintly orange powder
The Uses of 3-Chloro-4-fluorophenylboronic acid
3-Chloro-4-fluorophenylboronic Acid is a reactant that has been used in the synthesis of 2-bromo-3-hexyl-5-(4-iodophenyl)thiophene, which has shown high anti-thrombolytic activity.
The Uses of 3-Chloro-4-fluorophenylboronic acid
suzuki reaction
The Uses of 3-Chloro-4-fluorophenylboronic acid
Reactant for:
- Rh-catalyzed asymmetric addition reactions
- Palladium-catalyzed oxidative cross-coupling reaction
- Suzuki-Miyaura coupling
Properties of 3-Chloro-4-fluorophenylboronic acid
| Melting point: | 242-247 °C (lit.) |
| Boiling point: | 306.0±52.0 °C(Predicted) |
| Density | 1.41±0.1 g/cm3(Predicted) |
| storage temp. | Inert atmosphere,2-8°C |
| solubility | soluble in Methanol |
| form | Powder |
| pka | 7?+-.0.10(Predicted) |
| color | Off-white to faintly orange |
| BRN | 7369789 |
| CAS DataBase Reference | 144432-85-9(CAS DataBase Reference) |
Safety information for 3-Chloro-4-fluorophenylboronic acid
| Signal word | Warning |
| Pictogram(s) |
![]() Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up. |
Computed Descriptors for 3-Chloro-4-fluorophenylboronic acid
3-Chloro-4-fluorophenylboronic acid manufacturer
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