3-Amino-2(1H)-pyridinone
- CAS NO.：33630-99-8
- Empirical Formula: C5H6N2O
- Molecular Weight: 110.11
- MDL number: MFCD03411556
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-05-28 05:35:53
What is 3-Amino-2(1H)-pyridinone?
Chemical properties
Brown to off-white crystalline powder.
The Uses of 3-Amino-2(1H)-pyridinone
It is used as pharmaceutical intermediate. It is involved in synthesis of functionalized pyrido[4,3-b][1,4]oxazine and imidazo[1,2-a]pyridine derivatives. The use of ethyl 2-chloro-3-oxopropanoate with 2-amino-3-hydroxypyridine or 3-amino-4-hydroxypyridine led, respectively, to imidazo[1,2-a]pyridine derivatives or ethyl pyrido[4,3-b][1,4] oxazine-2-carboxylate.
Properties of 3-Amino-2(1H)-pyridinone
| Melting point: | 118-130 °C |
| Boiling point: | 206.4°C (rough estimate) |
| Density | 1.2111 (rough estimate) |
| refractive index | 1.4800 (estimate) |
| storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C |
| form | Powder |
| pka | 13.87±0.10(Predicted) |
| color | Dark brown to black |
| Water Solubility | Slightly soluble in water. |
| CAS DataBase Reference | 33630-99-8(CAS DataBase Reference) |
Safety information for 3-Amino-2(1H)-pyridinone
| Signal word | Danger |
| Pictogram(s) |
 Corrosion Corrosives GHS05  Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H318:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 3-Amino-2(1H)-pyridinone
3-Amino-2(1H)-pyridinone manufacturer
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product: 3-Amino-2-Hydroxypyridine 99%
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