3-[2-N-(BIOTINYL)AMINOETHYLDITHIO]PROPANOIC ACID
Synonym(s):3-((2-(5-((3aS,4S,6aR)-2-Oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamido)ethyl)disulfaneyl)propanoic acid;Biotin-SS-COOH;Cleavable biotin linker
- CAS NO.:104582-29-8
- Empirical Formula: C15H25N3O4S3
- Molecular Weight: 407.57
- MDL number: MFCD04039425
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-04-24 14:58:37
What is 3-[2-N-(BIOTINYL)AMINOETHYLDITHIO]PROPANOIC ACID?
Chemical properties
White Powder
The Uses of 3-[2-N-(BIOTINYL)AMINOETHYLDITHIO]PROPANOIC ACID
3-[2-N-(Biotinyl)aminoethyldithio]propanoic acid (Biotin-SS-COOH) is a cleavable, biotinylated crosslinkers. The linker can also be used for synthesis of chemical biology tools for labeling target proteins in biological experiments and assays. It possesses dual functionality: enrichment via the biotin and an embedded disulfide bridge for cleavage under reducing conditions.
What are the applications of Application
3-[2-N-(Biotinyl)aminoethyldithio]propanoic Acid is used in the production of cleavable biotin-conjugated haptens
Properties of 3-[2-N-(BIOTINYL)AMINOETHYLDITHIO]PROPANOIC ACID
| Melting point: | 173-175°C |
| Boiling point: | 772.4±60.0 °C(Predicted) |
| Density | 1.318±0.06 g/cm3(Predicted) |
| storage temp. | -20°C Freezer |
| solubility | Aqueous Base (Slightly), DMSO (Slightly) |
| form | Solid |
| pka | 4.25±0.10(Predicted) |
| color | White to Beige |
Safety information for 3-[2-N-(BIOTINYL)AMINOETHYLDITHIO]PROPANOIC ACID
Computed Descriptors for 3-[2-N-(BIOTINYL)AMINOETHYLDITHIO]PROPANOIC ACID
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![1H-Thieno[3,4-d]iMidazole-4-pentanaMide, hexahydro-N-[2-(4-hydroxyphenyl)ethyl]-2-oxo-, (3aS,4S,6aR)-](https://img.chemicalbook.in/CAS/GIF/41994-02-9.gif)

![1H-Thieno[3,4-d]iMidazole-4-pentanaMide, hexahydro-2-oxo-N-2-propynyl-, (3aS,4S,6aR)-](https://img.chemicalbook.in/CAS/GIF/773888-45-2.gif)
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