3-(2-HYDROXYPHENYL)PROPIONIC ACID

CAS NO.：495-78-3
Empirical Formula: C9H10O3
Molecular Weight: 166.17
MDL number: MFCD00014026
SAFETY DATA SHEET (SDS)
Update Date: 2025-09-05 20:24:49

What is 3-(2-HYDROXYPHENYL)PROPIONIC ACID?

The Uses of 3-(2-HYDROXYPHENYL)PROPIONIC ACID

3-(2-Hydroxyphenyl)propionic acid is suitable as a growth substrate for various strains of E. coli and as a standard in the study of microbial metabolism of catechin stereoisomers.

Definition

ChEBI: A monocarboxylic acid that is propionic acid in which one of the hydrogens at position 3 is substituted by a 2-hydroxyphenyl group.

General Description

3-(2-Hydroxyphenyl) propionic acid is a phenyl propionic acid derivative. It was found to be one of the constituents of Justicia pectoralis Jacq. extract which was analyzed by gas chromatography/mass spectrometry (GC/MS). The antiulcerogenic effect of 3-(2-hydroxyphenyl) propionic acid in the prevention of serotonin-induced ulcerogenesis has been studied in rats. It has been reported to be one of the major microbial metabolite of both (+)-catechin and (-)-epicatechin by human faecal microbiota. Crystal structure study reveals that 3-(2-hydroxyphenyl)propionic acid crystals are monoclinic with space group P2₁/c.

Properties of 3-(2-HYDROXYPHENYL)PROPIONIC ACID

Melting point:	86-89 °C(lit.)
Boiling point:	335.9±17.0 °C(Predicted)
Density	1.260±0.06 g/cm3(Predicted)
storage temp.	Sealed in dry,Room Temperature
solubility	Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
form	Solid
pka	4.75±0.10(Predicted)
color	Pale Yellow
BRN	1681601
Stability:	Hygroscopic
CAS DataBase Reference	495-78-3(CAS DataBase Reference)
EPA Substance Registry System	Benzenepropanoic acid, 2-hydroxy- (495-78-3)

Safety information for 3-(2-HYDROXYPHENYL)PROPIONIC ACID

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.