3-(2-FURANYLMETHYL)-3,7-DIHYDRO-1,8-DIMETHYL-1H-PURINE-2,6-DIONE
Synonym(s):3-(2-Furanylmethyl)-3,7-dihydro-1,8-dimethyl-1H-purine-2,6-dione
- CAS NO.：80288-49-9
- Empirical Formula: C12H12N4O3
- Molecular Weight: 260.25
- MDL number: MFCD00153799
- EINECS: 200-158-5
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-12-07 19:09:50
What is 3-(2-FURANYLMETHYL)-3,7-DIHYDRO-1,8-DIMETHYL-1H-PURINE-2,6-DIONE?
The Uses of 3-(2-FURANYLMETHYL)-3,7-DIHYDRO-1,8-DIMETHYL-1H-PURINE-2,6-DIONE
inhibitor
The Uses of 3-(2-FURANYLMETHYL)-3,7-DIHYDRO-1,8-DIMETHYL-1H-PURINE-2,6-DIONE
Furafylline is a selective inhibitor of human cytochrome P450. It is also reported to inhibit the oxidation of caffeine.
What are the applications of Application
Furafylline is an inhibitor of Cytochrome P450 (CYP1A2) and phosphodiesterase (PDE)
Definition
ChEBI: Furafylline is an oxopurine.
Biochem/physiol Actions
Furafylline (1,8-dimethyl-3-(2′ -furfuryl)methylxanthine) is a xanthine derivative. It is preferred in treating asthma. It serves as a N3-demethylation inhibitor of caffeine. Furafylline does not show much effect on human monooxygenase activities. It is considered as an efficient bronchodilator and as an inhibitor of anaphylactic reactions, when compared to theophylline.
Properties of 3-(2-FURANYLMETHYL)-3,7-DIHYDRO-1,8-DIMETHYL-1H-PURINE-2,6-DIONE
| Melting point: | >162°C (dec.) |
| Boiling point: | 543.6±60.0 °C(Predicted) |
| Density | 1.443±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C(protect from light) |
| solubility | ethanol: 0.33 mg/mL |
| form | solid |
| pka | 8.62±0.70(Predicted) |
| color | white |
Safety information for 3-(2-FURANYLMETHYL)-3,7-DIHYDRO-1,8-DIMETHYL-1H-PURINE-2,6-DIONE
Computed Descriptors for 3-(2-FURANYLMETHYL)-3,7-DIHYDRO-1,8-DIMETHYL-1H-PURINE-2,6-DIONE
| InChIKey | KGQZGCIVHYLPBH-UHFFFAOYSA-N |
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