(2S)-5,7-Dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-4-chromanone, 3',5,7-Trihydroxy-4-methoxyflavanone

Synonym(s):3′,5,7-Trihydroxy-4′-methoxyflavanone;5,7-Dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-4-chromanone;Hesperetin

CAS NO.：69097-99-0
Empirical Formula: C16H14O6
Molecular Weight: 302.28
MDL number: MFCD00016956
SAFETY DATA SHEET (SDS)
Update Date: 2026-05-28 05:59:41

(2S)-5,7-Dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-4-chromanone, 3',5,7-Trihydroxy-4-methoxyflavanone Structural

What is (2S)-5,7-Dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-4-chromanone, 3',5,7-Trihydroxy-4-methoxyflavanone?

The Uses of (2S)-5,7-Dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-4-chromanone, 3',5,7-Trihydroxy-4-methoxyflavanone

Hesperetin has been used as a standard in studies involving the cytotoxic effect of hesperetin on doxorubicin-resistant MCF-7 cells using enzyme-linked immunosorbent assay (ELISA) technique.

What are the applications of Application

Hesperetin is a dietary flavanone with chemopreventive effect

Definition

ChEBI: 5,7-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-3,4-dihydro-2H-1-benzopyran-4-one is an ether and a member of flavonoids.

General Description

Hesperetin is an aglycon form of flavonoid, which can be found in peels of citrus fruits.

Biochem/physiol Actions

Dietary flavanone with chemopreventive effect.

Properties of (2S)-5,7-Dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-4-chromanone, 3',5,7-Trihydroxy-4-methoxyflavanone

Melting point:	227-232°C
Boiling point:	586.2±50.0 °C(Predicted)
Density	1.458±0.06 g/cm3(Predicted)
FEMA	4313 \| 5,7-DIHYDROXY-2-(3-HYDROXY-4-METHOXYPHENYL)CHROMAN-4-ONE
storage temp.	2-8°C
solubility	ethanol: soluble50mg/mL, clear to almost clear, colorless to slightly yellow
form	powder (with a light tan cast)
pka	7.49±0.40(Predicted)
color	Pale Yellow to Light Brown
JECFA Number	2024

Safety information for (2S)-5,7-Dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-4-chromanone, 3',5,7-Trihydroxy-4-methoxyflavanone

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation
Precautionary Statement Codes	P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P332+P313:IF SKIN irritation occurs: Get medical advice/attention. P337+P313:IF eye irritation persists: Get medical advice/attention.

Computed Descriptors for (2S)-5,7-Dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-4-chromanone, 3',5,7-Trihydroxy-4-methoxyflavanone

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