Contact us: +91 9550333722 040 - 40102781
Structured search
India
Choose your country
Different countries will display different contents
Try our best to find the right business for you.
My chemicalbook

Welcome back!

HomeProduct name list7-HYDROXYFLAVONE

7-HYDROXYFLAVONE

Synonym(s):7-Hydroxy-2-phenyl-4H-1-benzopyran-4-one;NSC 94258

  • CAS NO.:6665-86-7
  • Empirical Formula: C15H10O3
  • Molecular Weight: 238.24
  • MDL number: MFCD00006835
  • EINECS: 229-705-3
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2023-08-17 16:10:33
7-HYDROXYFLAVONE Structural

What is 7-HYDROXYFLAVONE?

Chemical properties

off-white crystals

The Uses of 7-HYDROXYFLAVONE

antifungal, analgesic

The Uses of 7-HYDROXYFLAVONE

Reactant:

  • Acting as a biologically valuable acceptor in O-glycosidation reactions
  • Involved in synthesis of fully phosphorylated flavones for use as pancreatic cholesterol esterase inhibitors
  • For O-methylation with di-Me carbonate
  • Linked by a polymethylene chain for synthesis of α1-adrenoceptor antagonists
  • Involved in Baylis-Hillman reactions
  • Involved in phase-transfer catalyzed glucosylation for synthesis of glucosylated flavonoids

What are the applications of Application

7-Hydroxyflavone is involved in synthesis of fully phosphorylated flavones

Definition

ChEBI: 7-hydroxyflavone is a hydroxyflavonoid in which the flavone nucleus is substituted at position 7 by a hydroxy group.

Synthesis Reference(s)

Tetrahedron Letters, 31, p. 6497, 1990 DOI: 10.1016/S0040-4039(00)97100-4

Biological Activity

7-Hydroxyflavone is a flavonoid isolated from M. indica with anti-inflammatory properties. It protects renal cells from nicotine (NIC)-induced cytotoxicity through the ERK/Nrf2/HO-1 pathway.

Properties of 7-HYDROXYFLAVONE

Melting point: 245-247 °C (lit.)
Boiling point: 320.83°C (rough estimate)
Density  1.340±0.06 g/cm3 (20 ºC 760 Torr)
refractive index  1.5740 (estimate)
solubility  Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Water Solubility  Insoluble in water
pka 7.02±0.40(Predicted)
form  powder to crystal
color  White to Light yellow
BRN  194089
CAS DataBase Reference 6665-86-7(CAS DataBase Reference)

Safety information for 7-HYDROXYFLAVONE

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P264:Wash hands thoroughly after handling.
P264:Wash skin thouroughly after handling.
P271:Use only outdoors or in a well-ventilated area.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352:IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for 7-HYDROXYFLAVONE

Related products of tetrahydrofuran

You may like

Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.