2H-Pyran, 2-[2-[2-(2-bromoethoxy)ethoxy]ethoxy]tetrahydro-

CAS NO.：220568-33-2
Empirical Formula: C11H21BrO4
Molecular Weight: 297.19
Update Date: 2026-03-18 11:52:23

What is 2H-Pyran, 2-[2-[2-(2-bromoethoxy)ethoxy]ethoxy]tetrahydro-?

Biological Activity

Bromo-PEG3-THP is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Properties of 2H-Pyran, 2-[2-[2-(2-bromoethoxy)ethoxy]ethoxy]tetrahydro-

Boiling point:	361.7±42.0 °C(Predicted)
Density	1.28±0.1 g/cm3(Predicted)

Safety information for 2H-Pyran, 2-[2-[2-(2-bromoethoxy)ethoxy]ethoxy]tetrahydro-

Computed Descriptors for 2H-Pyran, 2-[2-[2-(2-bromoethoxy)ethoxy]ethoxy]tetrahydro-

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