2',7'-DIFLUOROFLUORESCEIN

What is 2',7'-DIFLUOROFLUORESCEIN?

2'',7''-Difluorofluorescein is a reactant used in the synthesis of biarsenical probes that inhibit protein tyrosine phosphatases.

Boiling point:	591.7±50.0 °C(Predicted)
Density	1.70±0.1 g/cm3(Predicted)
solubility	Insoluble in water; soluble in N,Ndimethylformamide
form	A solid
pka	4.8, (at 22℃);4.7, (at 22℃)
color	Orange powder
λmax	490 nm (Buffer pH 9.0)
Major Application	As geothermal tracers;TiO2 nanoparticles for light energy conversion
Biological Applications	Detecting atherosclerosis;detecting/monitoring amyloid Aβ production/accumulation/aggregation/disaggregation; diagnosing Alzheimer’s disease;estimating/measuring concentration of cortisol, melatonin, secretory IgA in body fluids;11 evaluating cetuximab-based imaging probe to target epidermal growth factor receptor (EGFR);examining biodistribution of proteins;investigating/measuring protein-protein and protein-nucleic acid interactions;measuring pH of apoplast at the root surface;visualizing hair follicles;as a substrate for measuring β-lactamase activity,phosphatases activity

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.