2,6-Dioxopiperidine-3-ammonium chloride
- CAS NO.：24666-56-6
- Empirical Formula: C5H9ClN2O2
- Molecular Weight: 164.59016
- MDL number: MFCD11042437
- EINECS: 807-866-6
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-04-17 18:45:41
What is 2,6-Dioxopiperidine-3-ammonium chloride?
Chemical properties
White crystal
Description
2,6-Dioxopiperidine-3-ammonium chloride is a reagent for preparing lenalidomide that can induce ubiquitination and degradation of CK1&alpha. It can also be used to prepare phthalimide conjugates that can promote ligand-dependent target protein degradation. Moreover, it is also a metabolite of thalidomide (T338850) that inhibits FGF-induced angiogenesis.
The Uses of 2,6-Dioxopiperidine-3-ammonium chloride
2,6-Dioxopiperidine-3-ammonium chloride can be used as an important intermediate of antineoplastic drug lenalidomide.
Properties of 2,6-Dioxopiperidine-3-ammonium chloride
| Melting point: | 120 °C (approx) |
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | DMSO (Slightly, Heated), Methanol (Sparingly, Sonicated) |
| color | White |
Safety information for 2,6-Dioxopiperidine-3-ammonium chloride
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. |
Computed Descriptors for 2,6-Dioxopiperidine-3-ammonium chloride
2,6-Dioxopiperidine-3-ammonium chloride manufacturer
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