2,6-Di-tert-butyl-4-methoxyphenol
Synonym(s):3,5-Di-tert-butyl-4-hydroxyanisole
- CAS NO.:489-01-0
- Empirical Formula: C15H24O2
- Molecular Weight: 236.35
- MDL number: MFCD00008824
- EINECS: 207-693-0
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-09-12 18:50:05
What is 2,6-Di-tert-butyl-4-methoxyphenol?
Chemical properties
white to beige crystalline powder
The Uses of 2,6-Di-tert-butyl-4-methoxyphenol
2,6-Di-tert-butyl-4-methoxyphenol has been used to protect cosmetics, drugs and foods from oxidative degradation.
Definition
ChEBI: 2,6-di-tert-butyl-4-methoxyphenol is a member of phenols and a member of methoxybenzenes.
General Description
2,6-Di-tert-butyl-4-methoxyphenol is a phenolic antioxidant. It participates in In(trifluoromethanesulfonate)3-catalyzed tandem reaction of ortho-alkynylarylimine with various nucleophiles.
Properties of 2,6-Di-tert-butyl-4-methoxyphenol
| Melting point: | 102-106 °C (lit.) |
| Boiling point: | 135-140°C 10mm |
| Density | 0.9845 (rough estimate) |
| refractive index | 1.5542 (estimate) |
| Flash point: | 135-140°C/10mm |
| solubility | soluble in Methanol |
| pka | 13.04±0.40(Predicted) |
| form | Liquid |
| color | Clear |
| BRN | 2052290 |
| CAS DataBase Reference | 489-01-0(CAS DataBase Reference) |
| EPA Substance Registry System | 2,6-Di-tert-butyl-4-methoxyphenol (489-01-0) |
Safety information for 2,6-Di-tert-butyl-4-methoxyphenol
| Signal word | Warning |
| Pictogram(s) |
![]() Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 2,6-Di-tert-butyl-4-methoxyphenol
New Products
Cyclobutanone (R)-(-)-2-Amino-1-propanol Fmoc-OSu 5-bromo-4-fluoro-2-nitrobenzaldehyde 2-Amino-2-(4-methylphenyl)acetic acid 1-(2-Chloroethyl)pyrrolidine Hydrochloride 2,4-Dihydroxybenzaldehyde Obidoxime hydrochloride API Pyrrolo[1,2-a]pyrimidine-6-carboxylic acid, 4,6,7,8-tetrahydro-4-oxo-, sodium salt (1:1), (6S) Dipropyl disulfide N-Vinylformamide 4 pentyn 1 ol Methacrylate-PEG-Methacrylate, Mn:35000 2,4-Dihydroxyacetophenone 2-Chloro 5-Fluoro Pyridine Vasicinone 2-Chloroisonicotinic Acid Tween 80 or Polysorbate 80 2-Butyn-1-oL N-(4-fluoro-2-methoxy-5-nitrophenyl)-4-(1-methyl-1H-indol-3-yl)pyrimidin-2-amine Pirtobrutinib intd. 2-Pentyn-1-oL 4-Nitrobenzotrifluoride N-(4-Cyano-3-(trifluoromethyl)phenyl)-2-methyloxirane-2-carboxamideRelated products of tetrahydrofuran








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